SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells

Multimodal single-cell RNA sequencing enables the precise mapping of transcriptional and phenotypic features of cellular differentiation states but does not allow for simultaneous integration of critical posttranslational modification data. Here, we describe SUrface-protein Glycan And RNA-seq (SUGAR...

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Publicat a:Sci Adv
Autors principals: Kearney, Conor J., Vervoort, Stephin J., Ramsbottom, Kelly M., Todorovski, Izabela, Lelliott, Emily J., Zethoven, Magnus, Pijpers, Lizzy, Martin, Ben P., Semple, Timothy, Martelotto, Luciano, Trapani, Joseph A., Parish, Ian A., Scott, Nichollas E., Oliaro, Jane, Johnstone, Ricky W.
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895430/
https://ncbi.nlm.nih.gov/pubmed/33608275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe3610
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