Lack of PRKD2 and PRKD3 kinase domain somatic mutations in PRKD1 wild-type classic polymorphous low-grade adenocarcinomas of the salivary gland

AIMS: Polymorphous low-grade adenocarcinoma (PLGA) is the second most common intra-oral salivary gland malignancy. The vast majority of PLGAs harbor a PRKD1 E710D hotspot somatic mutation or somatic rearrangements of PRKD1, PRKD2 or PRKD3. Given the kinase domain homology among PRKD1, PRKD2 and PRKD...

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Bibliografske podrobnosti
izdano v:Histopathology
Main Authors: Piscuoglio, Salvatore, Fusco, Nicola, Ng, Charlotte KY, Martelotto, Luciano G, da Cruz Paula, Arnaud, Katabi, Nora, Rubin, Brian P, Skálová, Alena, Weinreb, Ilan, Weigelt, Britta, Reis-Filho, Jorge S
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600617/
https://ncbi.nlm.nih.gov/pubmed/26426580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/his.12883
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