Genetic instability and recurrent MYC amplification in ALK‐translocated NSCLC: a central role of TP53 mutations

The anaplastic lymphoma kinase (ALK) rearrangement defines a distinct molecular subtype of non‐small cell lung cancer (NSCLC). Despite the excellent initial efficacy of ALK inhibitors in patients with ALK+ lung cancer, resistance occurs almost inevitably. To date, there is no reliable biomarker allo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Pathol
Egile Nagusiak: Alidousty, Christina, Baar, Till, Martelotto, Luciano G, Heydt, Carina, Wagener, Svenja, Fassunke, Jana, Duerbaum, Nicolai, Scheel, Andreas H, Frank, Sandra, Holz, Barbara, Binot, Elke, Kron, Anna, Merkelbach‐Bruse, Sabine, Ihle, Michaela A, Wolf, Jürgen, Buettner, Reinhard, Schultheis, Anne Maria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Ltd 2018
Gaiak:
Original Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120547/
https://ncbi.nlm.nih.gov/pubmed/29885057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5110
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