Genetic instability and recurrent MYC amplification in ALK‐translocated NSCLC: a central role of TP53 mutations

The anaplastic lymphoma kinase (ALK) rearrangement defines a distinct molecular subtype of non‐small cell lung cancer (NSCLC). Despite the excellent initial efficacy of ALK inhibitors in patients with ALK+ lung cancer, resistance occurs almost inevitably. To date, there is no reliable biomarker allo...

詳細記述

保存先:
書誌詳細
出版年:J Pathol
主要な著者: Alidousty, Christina, Baar, Till, Martelotto, Luciano G, Heydt, Carina, Wagener, Svenja, Fassunke, Jana, Duerbaum, Nicolai, Scheel, Andreas H, Frank, Sandra, Holz, Barbara, Binot, Elke, Kron, Anna, Merkelbach‐Bruse, Sabine, Ihle, Michaela A, Wolf, Jürgen, Buettner, Reinhard, Schultheis, Anne Maria
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Ltd 2018
主題:
Original Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120547/
https://ncbi.nlm.nih.gov/pubmed/29885057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5110
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