Genomic Characterization of TP53–Wild-Type Esophageal Carcinoma()

Up to 40% of esophageal carcinomas have a biallelic intact TP53 gene. It is largely unclear how these carcinoma cells prevent apoptosis, what is the kind of pathway alterations, or whether therapeutically relevant alterations exist in this subgroup. We evaluated The Cancer Genome Atlas (TCGA) data t...

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Bibliografski detalji
Izdano u:Transl Oncol
Glavni autori: Quaas, Alexander, Heydt, Carina, Gebauer, Florian, Alakus, Hakan, Loeser, Heike, Buettner, Reinhard, Hillmer, Axel, Bruns, Christiane, Merkelbach-Bruse, Sabine, Zander, Thomas, Frommolt, Peter
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press 2018
Teme:
Original article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187090/
https://ncbi.nlm.nih.gov/pubmed/30317074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.09.007
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