Genomic Characterization of TP53–Wild-Type Esophageal Carcinoma()

Up to 40% of esophageal carcinomas have a biallelic intact TP53 gene. It is largely unclear how these carcinoma cells prevent apoptosis, what is the kind of pathway alterations, or whether therapeutically relevant alterations exist in this subgroup. We evaluated The Cancer Genome Atlas (TCGA) data t...

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Bibliografiske detaljer
Udgivet i:Transl Oncol
Main Authors: Quaas, Alexander, Heydt, Carina, Gebauer, Florian, Alakus, Hakan, Loeser, Heike, Buettner, Reinhard, Hillmer, Axel, Bruns, Christiane, Merkelbach-Bruse, Sabine, Zander, Thomas, Frommolt, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2018
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Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187090/
https://ncbi.nlm.nih.gov/pubmed/30317074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.09.007
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