Genomic Characterization of TP53–Wild-Type Esophageal Carcinoma()

Up to 40% of esophageal carcinomas have a biallelic intact TP53 gene. It is largely unclear how these carcinoma cells prevent apoptosis, what is the kind of pathway alterations, or whether therapeutically relevant alterations exist in this subgroup. We evaluated The Cancer Genome Atlas (TCGA) data t...

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Publicat a:Transl Oncol
Autors principals: Quaas, Alexander, Heydt, Carina, Gebauer, Florian, Alakus, Hakan, Loeser, Heike, Buettner, Reinhard, Hillmer, Axel, Bruns, Christiane, Merkelbach-Bruse, Sabine, Zander, Thomas, Frommolt, Peter
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2018
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187090/
https://ncbi.nlm.nih.gov/pubmed/30317074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.09.007
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