Genomic Characterization of TP53–Wild-Type Esophageal Carcinoma()

Up to 40% of esophageal carcinomas have a biallelic intact TP53 gene. It is largely unclear how these carcinoma cells prevent apoptosis, what is the kind of pathway alterations, or whether therapeutically relevant alterations exist in this subgroup. We evaluated The Cancer Genome Atlas (TCGA) data t...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Quaas, Alexander, Heydt, Carina, Gebauer, Florian, Alakus, Hakan, Loeser, Heike, Buettner, Reinhard, Hillmer, Axel, Bruns, Christiane, Merkelbach-Bruse, Sabine, Zander, Thomas, Frommolt, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187090/
https://ncbi.nlm.nih.gov/pubmed/30317074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.09.007
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