Genomic Characterization of TP53–Wild-Type Esophageal Carcinoma()

Up to 40% of esophageal carcinomas have a biallelic intact TP53 gene. It is largely unclear how these carcinoma cells prevent apoptosis, what is the kind of pathway alterations, or whether therapeutically relevant alterations exist in this subgroup. We evaluated The Cancer Genome Atlas (TCGA) data t...

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Bibliografiska uppgifter
I publikationen:Transl Oncol
Huvudupphovsmän: Quaas, Alexander, Heydt, Carina, Gebauer, Florian, Alakus, Hakan, Loeser, Heike, Buettner, Reinhard, Hillmer, Axel, Bruns, Christiane, Merkelbach-Bruse, Sabine, Zander, Thomas, Frommolt, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press 2018
Ämnen:
Original article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187090/
https://ncbi.nlm.nih.gov/pubmed/30317074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.09.007
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