Hepatocellular Carcinoma: Updates in Pathogenesis, Detection and Treatment

Por Martínez-Chantar, Maria L., Avila, Matias A., Lu, Shelly C.
Publicado no Cancers (Basel) (2020)

S-Adenosylmethionine regulates Connexins sub-types expressed by hepatocytes

Por Yamaji, Sachie, Droggiti, Anna, Lu, Shelly C., Martinez-Chantar, Maria L., Warner, Anne, Varela-Rey, Marta
Publicado em 2010

INHIBITION OF NK CELLS PROTECTS THE LIVER AGAINST ACUTE INJURY IN THE ABSENCE OF GNMT

Por Gomez-Santos, Laura, Luka, Zigmund, Wagner, Conrad, Fernandez-Alvarez, Sara, Lu, Shelly C, Mato, Jose M, Martinez-Chantar, Maria L, Beraza, Naiara
Publicado em 2012

Inhibiting expression of specific genes in mammalian cells with 5′ end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA

Por Fortes, Puri, Cuevas, Yolanda, Guan, Fei, Liu, Peng, Pentlicky, Sara, Jung, Stephen P., Martínez-Chantar, Maria L., Prieto, Jesús, Rowe, David, Gunderson, Samuel I.
Publicado em 2003

GRK2-Dependent HuR Phosphorylation Regulates HIF1α Activation under Hypoxia or Adrenergic Stress

Por Reglero, Clara, Lafarga, Vanesa, Rivas, Verónica, Albitre, Ángela, Ramos, Paula, Berciano, Susana R., Tapia, Olga, Martínez-Chantar, María L., Mayor Jr, Federico, Penela, Petronila
Publicado no Cancers (Basel) (2020)

Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease

Por Dushay, Jody, Chui, Patricia C, Gopalakrishnan, Gosala S, Varela-Rey, Marta, Crawley, Meghan, Fisher, ffolliott M, Badman, Michael K, Martinez-Chantar, Maria L, Maratos-Flier, Eleftheria
Publicado no Gastroenterology (2010)

High-frequency ultrasound imaging for longitudinal evaluation of non-alcoholic fatty liver disease progression in mice

Por Fernández-Domínguez, Itziar, Echevarria-Uraga, J Javier, Gómez, Nieves, Luka, Zigmund, Wagner, Conrad, Lu, Shelly C, Mato, José M, Martínez-Chantar, Maria L, Rodríguez-Cuesta, Juan
Publicado em 2011

Methionine Adenosyltransferase 2B, HuR, and Sirtuin 1 Protein Cross-talk Impacts on the Effect of Resveratrol on Apoptosis and Growth in Liver Cancer Cells

Por Yang, Heping, Zheng, Yuhua, Li, Tony W. H., Peng, Hui, Fernandez-Ramos, David, Martínez-Chantar, María L., Rojas, Adriana L., Mato, José M., Lu, Shelly C.
Publicado em 2013

Methionine adenosyltransferase 2B, HuR, and sirtuin 1 protein cross-talk impacts on the effect of resveratrol on apoptosis and growth in liver cancer cells.

Por Yang, Heping, Zheng, Yuhua, Li, Tony W. H., Peng, Hui, Fernandez-Ramos, David, Martínez-Chantar, María L., Rojas, Adriana L., Mato, José M., Lu, Shelly C.
Publicado em 2014

The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets

Por Scheiba, Rafael M, de Opakua, Alain Ibáñez, Díaz-Quintana, Antonio, Cruz-Gallardo, Isabel, Martínez-Cruz, Luis A, Martínez-Chantar, María L, Blanco, Francisco J, Díaz-Moreno, Irene
Publicado no RNA Biol (2015)

Proteomic Profiling of Adipose Tissue from Zmpste24(−/−) Mice, a Model of Lipodystrophy and Premature Aging, Reveals Major Changes in Mitochondrial Function and Vimentin Processing...

Por Peinado, Juan R., Quirós, Pedro M., Pulido, Marina R., Mariño, Guillermo, Martínez-Chantar, Maria L., Vázquez-Martínez, Rafael, Freije, José M. P., López-Otín, Carlos, Malagón, María M.
Publicado em 2011

Targeting of Gamma-Glutamyl-Cysteine Ligase by miR-433 Reduces Glutathione Biosynthesis and Promotes TGF-β-Dependent Fibrogenesis

Por Espinosa-Diez, Cristina, Fierro-Fernández, Marta, Sánchez-Gómez, Francisco, Rodríguez-Pascual, Fernando, Alique, Matilde, Ruiz-Ortega, Marta, Beraza, Naiara, Martínez-Chantar, Maria L., Fernández-Hernando, Carlos, Lamas, Santiago
Publicado no Antioxid Redox Signal (2015)

HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs

Por Pabis, Marta, Popowicz, Grzegorz M, Stehle, Ralf, Fernández-Ramos, David, Asami, Sam, Warner, Lisa, García-Mauriño, Sofía M, Schlundt, Andreas, Martínez-Chantar, María L, Díaz-Moreno, Irene, Sattler, Michael
Publicado no Nucleic Acids Res (2019)

Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance

Por Carrasco, Manuel, Rabaneda, Luis G., Murillo-Carretero, Maribel, Ortega-Martínez, Sylvia, Martínez-Chantar, María L., Woodhoo, Ashwin, Luka, Zigmund, Wagner, Conrad, Lu, Shelly C., Mato, José M., Micó, Juan A., Castro, Carmen
Publicado em 2014

Obese patients with NASH have increased hepatic expression of SARS-CoV-2 critical entry points

Por Fondevila, Marcos F., Mercado-Gómez, Maria, Rodríguez, Amaia, Gonzalez-Rellan, Maria J., Iruzubieta, Paula, Valentí, Víctor, Escalada, Javier, Schwaninger, Markus, Prevot, Vincent, Dieguez, Carlos, Crespo, Javier, Frühbeck, Gema, Martinez-Chantar, Maria L., Nogueiras, Ruben
Publicado no J Hepatol (2021)

Id2 leaves the chromatin of the E2F4–p130-controlled c-myc promoter during hepatocyte priming for liver regeneration

Por Rodríguez, José L., Sandoval, Juan, Serviddio, Gaetano, Sastre, Juan, Morante, María, Perrelli, Maria-Giulia, Martínez-Chantar, María L., Viña, José, Viña, Juan R., Mato, José M., Ávila, Matías A., Franco, Luis, López-Rodas, Gerardo, Torres, Luis
Publicado em 2006

Activation of LKB1-Akt pathway independent of PI3 Kinase plays a critical role in the proliferation of hepatocellular carcinoma from NASH

Por Martínez-López, Nuria, Varela-Rey, Marta, Fernández-Ramos, David, Woodhoo, Ashwin, Vázquez-Chantada, Mercedes, Embade, Nieves, Espinosa-Hevia, Luis, Bustamante, Francisco Javier, Parada, Luis A, Rodriguez, Manuel S, Lu, Shelly C, Mato, José M, Martínez-Chantar, Maria L
Publicado em 2010

The Promyelocytic Leukemia Protein Is Upregulated in Conditions of Obesity and Liver Steatosis

Por Carracedo, Arkaitz, Rousseau, Déborah, Douris, Nicholas, Fernández-Ruiz, Sonia, Martín-Martín, Natalia, Weiss, Dror, Webster, Kaitlyn, Adams, Andrew C., Vazquez-Chantada, Mercedes, Martinez-Chantar, Maria L., Anty, Rodolphe, Tran, Albert, Maratos-Flier, Eleftheria, Gual, Philippe, Pandolfi, Pier Paolo
Publicado no Int J Biol Sci (2015)

Epigenetic events involved in organic cation transporter 1‐dependent impaired response of hepatocellular carcinoma to sorafenib

Por Al‐Abdulla, Ruba, Lozano, Elisa, Macias, Rocio I R, Monte, Maria J, Briz, Oscar, O'Rourke, Colm J, Serrano, Maria A, Banales, Jesus M, Avila, Matias A, Martinez‐Chantar, Maria L, Geier, Andreas, Andersen, Jesper B, Marin, Jose J G
Publicado no Br J Pharmacol (2019)

Hepatoma Cells from Mice Deficient in Glycine N-Methyltransferase Have Increased RAS Signaling and Activation of Liver Kinase B1

Por Martínez-López, Nuria, García-Rodríguez, Juan L, Varela-Rey, Marta, Gutiérrez, Virginia, Fernández-Ramos, David, Beraza, Naiara, Aransay, Ana M, Schlangen, Karin, Lozano, Juan Jose, Aspichueta, Patricia, Luka, Zigmund, Wagner, Conrad, Evert, Matthias, Calvisi, Diego F, Lu, Shelly C, Mato, José M, Martínez-Chantar, María L
Publicado em 2012