A subset of dysregulated metabolic and survival genes is associated with severity of hepatic steatosis in obese Zucker rats

Por Buqué, Xabier, Martínez, María José, Cano, Ainara, Miquilena-Colina, María E., García-Monzón, Carmelo, Aspichueta, Patricia, Ochoa, Begoña
Publicado em 2010

High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway

Por Bravo, Elena, Palleschi, Simonetta, Aspichueta, Patricia, Buqué, Xabier, Rossi, Barbara, Cano, Ainara, Napolitano, Mariarosaria, Ochoa, Begoña, Botham, Kathleen M
Publicado em 2011

Methionine adenosyltransferase 1A gene deletion disrupts hepatic VLDL assembly in mice

Por Cano, Ainara, Buqué, Xabier, Martínez-Uña, Maite, Aurrekoetxea, Igor, Menor, Ariane, García-Rodriguez, Juan L, Lu, Shelly C, Martínez-Chantar, M. Luz, Mato, José M., Ochoa, Begoña, Aspichueta, Patricia
Publicado em 2011

SIRT1 controls liver regeneration by regulating BA metabolism through FXR and mTOR signaling

Por García-Rodríguez, Juan L., Barbier-Torres, Lucía, Fernández-Álvarez, Sara, Juan, Virginia Gutiérrez-de, Monte, María J., Halilbasic, Emina, Herranz, Daniel, Álvarez, Luis, Aspichueta, Patricia, Marín, Jose J. G., Trauner, Michael, Mato, Jose M., Serrano, Manuel, Beraza, Naiara, Martínez-Chantar, María Luz
Publicado em 2014

Hepatoma Cells from Mice Deficient in Glycine N-Methyltransferase Have Increased RAS Signaling and Activation of Liver Kinase B1

Por Martínez-López, Nuria, García-Rodríguez, Juan L, Varela-Rey, Marta, Gutiérrez, Virginia, Fernández-Ramos, David, Beraza, Naiara, Aransay, Ana M, Schlangen, Karin, Lozano, Juan Jose, Aspichueta, Patricia, Luka, Zigmund, Wagner, Conrad, Evert, Matthias, Calvisi, Diego F, Lu, Shelly C, Mato, José M, Martínez-Chantar, María L
Publicado em 2012

Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis

Por Martínez-Uña, Maite, Varela-Rey, Marta, Cano, Ainara, Fernández-Ares, Larraitz, Beraza, Naiara, Aurrekoetxea, Igor, Martínez-Arranz, Ibon, García-Rodríguez, Juan L, Buqué, Xabier, Mestre, Daniela, Luka, Zigmund, Wagner, Conrad, Alonso, Cristina, Finnell, Richard H, Lu, Shelly C, Martínez-Chantar, M Luz, Aspichueta, Patricia, Mato, José M
Publicado em 2013

S-adenosylmethionine increases circulating very-low density lipoprotein clearance in nonalcoholic fatty liver disease

Por Martinez-Una, Maite, Varela-Rey, Marta, Mestre, Daniela, Fernandez-Ares, Larraitz, Fresnedo, Olatz, Fernandez-Ramos, David, Juan, Virginia Gutierrez-de, Martin-Guerrero, Idoia, Garcia-Orad, Africa, Luka, Zigmund, Wagner, Conrad, Lu, Shelly C, Garcia-Monzon, Carmelo, Finnell, Richard H, Aurrekoetxea, Igor, Buque, Xabier, Martinez-Chantar, M. Luz, Mato, Jose M., Aspichueta, Patricia
Publicado no J Hepatol (2014)

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves

Por Gomez-Sanchez, Jose A., Carty, Lucy, Iruarrizaga-Lejarreta, Marta, Palomo-Irigoyen, Marta, Varela-Rey, Marta, Griffith, Megan, Hantke, Janina, Macias-Camara, Nuria, Azkargorta, Mikel, Aurrekoetxea, Igor, De Juan, Virginia Gutiérrez, Jefferies, Harold B.J., Aspichueta, Patricia, Elortza, Félix, Aransay, Ana M., Martínez-Chantar, María L., Baas, Frank, Mato, José M., Mirsky, Rhona, Woodhoo, Ashwin, Jessen, Kristján R.
Publicado no J Cell Biol (2015)

Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer

Por Barbier-Torres, Lucía, Delgado, Teresa C., García-Rodríguez, Juan L., Zubiete-Franco, Imanol, Fernández-Ramos, David, Buqué, Xabier, Cano, Ainara, Juan, Virginia Gutiérrez-de, Fernández-Domínguez, Itziar, Lopitz-Otsoa, Fernando, Fernández-Tussy, Pablo, Boix, Loreto, Bruix, Jordi, Villa, Erica, Castro, Azucena, Lu, Shelly C., Aspichueta, Patricia, Xirodimas, Dimitris, Varela-Rey, Marta, Mato, José M., Beraza, Naiara, Martínez-Chantar, María L.
Publicado no Oncotarget (2014)

Deregulated neddylation in liver fibrosis

Por Zubiete-Franco, Imanol, Fernández-Tussy, Pablo, Barbier-Torres, Lucía, Simon, Jorge, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Juan, Virginia Gutiérrez-de, de Davalillo, Sergio López, Duce, Antonio Martín, Iruzubieta, Paula, Taibo, Daniel, Crespo, Javier, Caballeria, Juan, Villa, Erica, Aurrekoetxea, Igor, Aspichueta, Patricia, Varela-Rey, Marta, Lu, Shelly C, Mato, José M, Beraza, Naiara, Delgado, Teresa C, Martínez-Chantar, María L
Publicado no Hepatology (2016)

Methionine and S-Adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis

Por Zubiete-Franco, Imanol, García-Rodríguez, Juan Luis, Martínez-Uña, Maite, Martínez-Lopez, Nuria, Woodhoo, Ashwin, Juan, Virginia Gutiérrez-De, Beraza, Naiara, Lage-Medina, Sergio, Andrade, Fernando, Fernandez, Marta Llarena, Aldámiz-Echevarría, Luis, Fernández-Ramos, David, Falcon-Perez, Juan Manuel, Lopitz-Otsoa, Fernando, Fernandez-Tussy, Pablo, Barbier-Torres, Lucía, Luka, Zigmund, Wagner, Conrad, García-Monzón, Carmelo, Lu, Shelly C., Aspichueta, Patricia, Mato, José María, Martínez-Chantar, María Luz, Varela-Rey, Marta
Publicado no J Hepatol (2015)