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High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway

BACKGROUND: Hyperhomocysteinemia (HHcy) causes increased oxidative stress and is an independent risk factor for cardiovascular disease. Oxidative stress is now believed to be a major contributory factor in the development of non alcoholic fatty liver disease, the most common liver disorder worldwide...

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Main Authors: Bravo, Elena, Palleschi, Simonetta, Aspichueta, Patricia, Buqué, Xabier, Rossi, Barbara, Cano, Ainara, Napolitano, Mariarosaria, Ochoa, Begoña, Botham, Kathleen M
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096990/
https://ncbi.nlm.nih.gov/pubmed/21504583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-10-60
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