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Deregulated neddylation in liver fibrosis

Hepatic fibrosis is a global health problem currently without effective therapeutic approaches. Even though the ubiquitin-like post-translational modification of neddylation, that conjugates Nedd8 to specific targets, is aberrant in many pathologies, its relevance in liver fibrosis remained unexplor...

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發表在:Hepatology
Main Authors: Zubiete-Franco, Imanol, Fernández-Tussy, Pablo, Barbier-Torres, Lucía, Simon, Jorge, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Juan, Virginia Gutiérrez-de, de Davalillo, Sergio López, Duce, Antonio Martín, Iruzubieta, Paula, Taibo, Daniel, Crespo, Javier, Caballeria, Juan, Villa, Erica, Aurrekoetxea, Igor, Aspichueta, Patricia, Varela-Rey, Marta, Lu, Shelly C, Mato, José M, Beraza, Naiara, Delgado, Teresa C, Martínez-Chantar, María L
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258821/
https://ncbi.nlm.nih.gov/pubmed/28035772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28933
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