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HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs
HuR/ELAVL1 is an RNA-binding protein involved in differentiation and stress response that acts primarily by stabilizing messenger RNA (mRNA) targets. HuR comprises three RNA recognition motifs (RRMs) where the structure and RNA binding of RRM3 and of full-length HuR remain poorly understood. Here, w...
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Published in: | Nucleic Acids Res |
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Main Authors: | , , , , , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
Oxford University Press
2019
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6344896/ https://ncbi.nlm.nih.gov/pubmed/30418581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1138 |
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