HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs

HuR/ELAVL1 is an RNA-binding protein involved in differentiation and stress response that acts primarily by stabilizing messenger RNA (mRNA) targets. HuR comprises three RNA recognition motifs (RRMs) where the structure and RNA binding of RRM3 and of full-length HuR remain poorly understood. Here, w...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Pabis, Marta, Popowicz, Grzegorz M, Stehle, Ralf, Fernández-Ramos, David, Asami, Sam, Warner, Lisa, García-Mauriño, Sofía M, Schlundt, Andreas, Martínez-Chantar, María L, Díaz-Moreno, Irene, Sattler, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
Предметы:
Structural Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344896/
https://ncbi.nlm.nih.gov/pubmed/30418581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1138
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы