Targeting the HuR oncogenic role with a new class of cytoplasmic dimerization inhibitors

The development of novel therapeutics that exploit alterations in the activation state of key cellular signaling pathways due to mutations in upstream regulators has generated the field of personalized medicine. These first-generation efforts have focused on actionable mutations identified by deep s...

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Publicado no:Cancer Res
Main Authors: Filippova, Natalia, Yang, Xiuhua, Ananthan, Subramaniam, Calano, Jennifer, Pathak, Vibha, Bratton, Larry, Vekariya, Rakesh H., Zhang, Sixue, Ofori, Edward, Hayward, Emily, Namkoong, David, Crossman, David K., Crowley, Michael R., King, Peter H., Mobley, James, Nabors, Louis B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8137579/
https://ncbi.nlm.nih.gov/pubmed/33602784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-2858
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