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HUR DEPENDENT REGULATION OF CENTROSOMES

BACKGROUND: The RNA-binding protein, HuR is over-expressed in glioma and controls mRNA stabilization and translation in centrosomes. Alterations in HuR phosphorylation promote centrosomal abnormalities. METHODS: Primary and established glioma cell lines were utilized. Subcellular fractionation and i...

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Detalhes bibliográficos
Main Authors: Nabors, Louis Burt, Filippova, Natalia, Yang, Xiuhua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144544/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.74
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