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Phosphoregulation of the RNA-binding Protein Hu Antigen R (HuR) by Cdk5 Affects Centrosome Function

Hu antigen R (HuR) is an mRNA-binding protein belonging to the ELAV family. It is highly expressed in cancer and involved in cell survival and proliferation. The impact of post-translational regulation of HuR and resulting cellular effects are poorly understood. In the current report, we describe a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Filippova, Natalia, Yang, Xiuhua, King, Peter, Nabors, L. Burt
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442558/
https://ncbi.nlm.nih.gov/pubmed/22829587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353912
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