In silico deconvolution and purification of cancer epigenomes

Por Duran-Ferrer, Martí, Beekman, Renée, Martín-Subero, José I.
Publicado no Oncoscience (2017)

DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights

Por Gómez, Soledad, Castellano, Giancarlo, Mayol, Gemma, Queiros, Ana, Martín-Subero, José I., Lavarino, Cinzia
Publicado no Genom Data (2015)

Pulmonary mucosa‐associated lymphoid tissue lymphoma with strong nuclear B‐cell CLL/lymphoma 10 (BCL10) expression and novel translocation t(1;2)(p22;p12)/immunoglobulin κ chain‐BC...

Por Chuang, Shih‐Sung, Liu, Hongxiang, Ye, Hongtao, Martín‐Subero, Jose I, Siebert, Reiner, Huang, Wen‐Tsung
Publicado em 2007

FISH Analysis for the Detection of Lymphoma-Associated Chromosomal Abnormalities in Routine Paraffin-Embedded Tissue

Por Ventura, Roland A., Martin-Subero, Jose I., Jones, Margaret, McParland, Joanna, Gesk, Stefan, Mason, David Y., Siebert, Reiner
Publicado em 2006

The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes

Por Subtil-Rodríguez, Alicia, Vázquez-Chávez, Elena, Ceballos-Chávez, María, Rodríguez-Paredes, Manuel, Martín-Subero, José I., Esteller, Manel, Reyes, José C.
Publicado em 2014

Array-based DNA methylation profiling of primary lymphomas of the central nervous system

Por Richter, Julia, Ammerpohl, Ole, Martín-Subero, José I, Montesinos-Rongen, Manuel, Bibikova, Marina, Wickham-Garcia, Eliza, Wiestler, Otmar D, Deckert, Martina, Siebert, Reiner
Publicado em 2009

DNA Hypomethylation Affects Cancer-Related Biological Functions and Genes Relevant in Neuroblastoma Pathogenesis

Por Mayol, Gemma, Martín-Subero, José I., Ríos, José, Queiros, Ana, Kulis, Marta, Suñol, Mariona, Esteller, Manel, Gómez, Soledad, Garcia, Idoia, de Torres, Carmen, Rodríguez, Eva, Galván, Patricia, Mora, Jaume, Lavarino, Cinzia
Publicado em 2012

Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures

Por Lee, Seung-Tae, Muench, Marcus O., Fomin, Marina E., Xiao, Jianqiao, Zhou, Mi, de Smith, Adam, Martín-Subero, José I., Heath, Simon, Houseman, E. Andres, Roy, Ritu, Wrensch, Margaret, Wiencke, John, Metayer, Catherine, Wiemels, Joseph L.
Publicado no Nucleic Acids Res (2015)

Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice

Por Fraile, Julia M., Campos-Iglesias, Diana, Rodríguez, Francisco, Astudillo, Aurora, Vilarrasa-Blasi, Roser, Verdaguer-Dot, Nuria, Prado, Miguel A., Paulo, Joao A., Gygi, Steven P., Martín-Subero, José I., Freije, José M. P., López-Otín, Carlos
Publicado no J Biol Chem (2018)

Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism

Por Kandaswamy, Radhika, Sava, Georgina P., Speedy, Helen E., Beà, Sílvia, Martín-Subero, José I., Studd, James B., Migliorini, Gabriele, Law, Philip J., Puente, Xose S., Martín-García, David, Salaverria, Itziar, Gutiérrez-Abril, Jesús, López-Otín, Carlos, Catovsky, Daniel, Allan, James M., Campo, Elías, Houlston, Richard S.
Publicado no Cell Rep (2016)

DNA methylation map of mouse and human brain identifies target genes in Alzheimer’s disease

Por Sanchez-Mut, Jose V., Aso, Ester, Panayotis, Nicolas, Lott, Ira, Dierssen, Mara, Rabano, Alberto, Urdinguio, Rocio G., Fernandez, Agustin F., Astudillo, Aurora, Martin-Subero, Jose I., Balint, Balazs, Fraga, Mario F., Gomez, Antonio, Gurnot, Cecile, Roux, Jean-Christophe, Avila, Jesus, Hensch, Takao K., Ferrer, Isidre, Esteller, Manel
Publicado em 2013

Aberrant epigenome in iPSC‐derived dopaminergic neurons from Parkinson's disease patients

Por Fernández‐Santiago, Rubén, Carballo‐Carbajal, Iria, Castellano, Giancarlo, Torrent, Roger, Richaud, Yvonne, Sánchez‐Danés, Adriana, Vilarrasa‐Blasi, Roser, Sánchez‐Pla, Alex, Mosquera, José Luis, Soriano, Jordi, López‐Barneo, José, Canals, Josep M, Alberch, Jordi, Raya, Ángel, Vila, Miquel, Consiglio, Antonella, Martín‐Subero, José I, Ezquerra, Mario, Tolosa, Eduardo
Publicado no EMBO Mol Med (2015)

Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems

Por Schuyler, Ronald P., Merkel, Angelika, Raineri, Emanuele, Altucci, Lucia, Vellenga, Edo, Martens, Joost H.A., Pourfarzad, Farzin, Kuijpers, Taco W., Burden, Frances, Farrow, Samantha, Downes, Kate, Ouwehand, Willem H., Clarke, Laura, Datta, Avik, Lowy, Ernesto, Flicek, Paul, Frontini, Mattia, Stunnenberg, Hendrik G., Martín-Subero, José I., Gut, Ivo, Heath, Simon
Publicado no Cell Rep (2016)

Epigenetic Activation of SOX11 in Lymphoid Neoplasms by Histone Modifications

Por Vegliante, Maria Carmela, Royo, Cristina, Palomero, Jara, Salaverria, Itziar, Balint, Balazs, Martín-Guerrero, Idoia, Agirre, Xabier, Lujambio, Amaia, Richter, Julia, Xargay-Torrent, Silvia, Bea, Silvia, Hernandez, Luis, Enjuanes, Anna, Calasanz, María José, Rosenwald, Andreas, Ott, German, Roman-Gomez, José, Prosper, Felipe, Esteller, Manel, Jares, Pedro, Siebert, Reiner, Campo, Elias, Martín-Subero, José I., Amador, Virginia
Publicado em 2011

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

Por San José-Enériz, Edurne, Agirre, Xabier, Rabal, Obdulia, Vilas-Zornoza, Amaia, Sanchez-Arias, Juan A., Miranda, Estibaliz, Ugarte, Ana, Roa, Sergio, Paiva, Bruno, Estella-Hermoso de Mendoza, Ander, Alvarez, Rosa María, Casares, Noelia, Segura, Victor, Martín-Subero, José I., Ogi, François-Xavier, Soule, Pierre, Santiveri, Clara M., Campos-Olivas, Ramón, Castellano, Giancarlo, de Barrena, Maite Garcia Fernandez, Rodriguez-Madoz, Juan Roberto, García-Barchino, Maria José, Lasarte, Juan Jose, Avila, Matias A, Martinez-Climent, Jose Angel, Oyarzabal, Julen, Prosper, Felipe
Publicado no Nat Commun (2017)

A Comprehensive Microarray-Based DNA Methylation Study of 367 Hematological Neoplasms

Por Martin-Subero, Jose I., Ammerpohl, Ole, Bibikova, Marina, Wickham-Garcia, Eliza, Agirre, Xabier, Alvarez, Sara, Brüggemann, Monika, Bug, Stefanie, Calasanz, Maria J., Deckert, Martina, Dreyling, Martin, Du, Ming Q., Dürig, Jan, Dyer, Martin J. S., Fan, Jian-Bing, Gesk, Stefan, Hansmann, Martin-Leo, Harder, Lana, Hartmann, Sylvia, Klapper, Wolfram, Küppers, Ralf, Montesinos-Rongen, Manuel, Nagel, Inga, Pott, Christiane, Richter, Julia, Román-Gómez, José, Seifert, Marc, Stein, Harald, Suela, Javier, Trümper, Lorenz, Vater, Inga, Prosper, Felipe, Haferlach, Claudia, Cigudosa, Juan Cruz, Siebert, Reiner
Publicado em 2009

Decoding the DNA methylome of mantle cell lymphoma in the light of the entire B cell lineage

Por Queirós, Ana C., Beekman, Renée, Vilarrasa-Blasi, Roser, Duran-Ferrer, Martí, Clot, Guillem, Merkel, Angelika, Raineri, Emanuele, Russiño, Nuria, Castellano, Giancarlo, Beà, Sílvia, Navarro, Alba, Kulis, Marta, Verdaguer-Dot, Núria, Jares, Pedro, Enjuanes, Anna, Calasanz, María José, Bergmann, Anke, Vater, Inga, Salaverría, Itziar, van de Werken, Harmen J. G., Wilson, Wyndham H., Datta, Avik, Flicek, Paul, Royo, Romina, Martens, Joost, Giné, Eva, Lopez-Guillermo, Armando, Stunnenberg, Hendrik G., Klapper, Wolfram, Pott, Christiane, Heath, Simon, Gut, Ivo G., Siebert, Reiner, Campo, Elías, Martín-Subero, José I.
Publicado no Cancer Cell (2016)

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers

Por Agirre, Xabier, Castellano, Giancarlo, Pascual, Marien, Heath, Simon, Kulis, Marta, Segura, Victor, Bergmann, Anke, Esteve, Anna, Merkel, Angelika, Raineri, Emanuele, Agueda, Lidia, Blanc, Julie, Richardson, David, Clarke, Laura, Datta, Avik, Russiñol, Nuria, Queirós, Ana C., Beekman, Renée, Rodríguez-Madoz, Juan R., José-Enériz, Edurne San, Fang, Fang, Gutiérrez, Norma C., García-Verdugo, José M., Robson, Michael I., Schirmer, Eric C., Guruceaga, Elisabeth, Martens, Joost H.A., Gut, Marta, Calasanz, Maria J., Flicek, Paul, Siebert, Reiner, Campo, Elías, Miguel, Jesús F. San, Melnick, Ari, Stunnenberg, Hendrik G., Gut, Ivo G., Prosper, Felipe, Martín-Subero, José I.
Publicado no Genome Res (2015)

Whole-genome fingerprint of the DNA methylome during human B-cell differentiation

Por Kulis, Marta, Merkel, Angelika, Heath, Simon, Queirós, Ana C., Schuyler, Ronald P., Castellano, Giancarlo, Beekman, Renée, Raineri, Emanuele, Esteve, Anna, Clot, Guillem, Verdaguer-Dot, Nuria, Duran-Ferrer, Martí, Russiñol, Nuria, Vilarrasa-Blasi, Roser, Ecker, Simone, Pancaldi, Vera, Rico, Daniel, Agueda, Lidia, Blanc, Julie, Richardson, David, Clarke, Laura, Datta, Avik, Pascual, Marien, Agirre, Xabier, Prosper, Felipe, Alignani, Diego, Paiva, Bruno, Caron, Gersende, Fest, Thierry, Muench, Marcus O., Fomin, Marina E., Lee, Seung-Tae, Wiemels, Joseph L., Valencia, Alfonso, Gut, Marta, Flicek, Paul, Stunnenberg, Hendrik G., Siebert, Reiner, Küppers, Ralf, Gut, Ivo G., Campo, Elías, Martín-Subero, José I.
Publicado no Nat Genet (2015)

Landscape of somatic mutations and clonal evolution in mantle cell lymphoma

Por Beà, Sílvia, Valdés-Mas, Rafael, Navarro, Alba, Salaverria, Itziar, Martín-Garcia, David, Jares, Pedro, Giné, Eva, Pinyol, Magda, Royo, Cristina, Nadeu, Ferran, Conde, Laura, Juan, Manel, Clot, Guillem, Vizán, Pedro, Di Croce, Luciano, Puente, Diana A., López-Guerra, Mónica, Moros, Alexandra, Roue, Gael, Aymerich, Marta, Villamor, Neus, Colomo, Lluís, Martínez, Antonio, Valera, Alexandra, Martín-Subero, José I., Amador, Virginia, Hernández, Luis, Rozman, Maria, Enjuanes, Anna, Forcada, Pilar, Muntañola, Ana, Hartmann, Elena M., Calasanz, María J., Rosenwald, Andreas, Ott, German, Hernández-Rivas, Jesús M., Klapper, Wolfram, Siebert, Reiner, Wiestner, Adrian, Wilson, Wyndham H., Colomer, Dolors, López-Guillermo, Armando, López-Otín, Carlos, Puente, Xose S., Campo, Elías
Publicado em 2013