Knockdown of USP18 Increases Alpha 2a Interferon Signaling and Induction of Interferon-Stimulating Genes but Does Not Increase Antiviral Activity in Huh7 Cells

ανά Murray, E. J., Burden, Frances, Horscroft, Nigel, Smith-Burchnell, Caroline, Westby, Mike
Έκδοση 2011

Deep Sequencing Insights in Therapeutic shRNA Processing and siRNA Target Cleavage Precision

ανά Denise, Hubert, Moschos, Sterghios A., Sidders, Benjamin, Burden, Frances, Perkins, Hannah, Carter, Nikki, Stroud, Tim, Kennedy, Michael, Fancy, Sally-Ann, Lapthorn, Cris, Lavender, Helen, Kinloch, Ross, Suhy, David, Corbau, Romu
Έκδοση 2014

In Vitro Characterization of the Activity of PF-05095808, a Novel Biological Agent for Hepatitis C Virus Therapy

ανά Lavender, Helen, Brady, Kevin, Burden, Frances, Delpuech-Adams, Oona, Denise, Hubert, Palmer, Amy, Perkins, Hannah, Savic, Boris, Scott, Sarah, Smith-Burchnell, Caroline, Troke, Phil, Wright, J. Fraser, Suhy, David, Corbau, Romu
Έκδοση 2012

Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia

ανά Bariana, Tadbir K., Labarque, Veerle, Heremans, Jessica, Thys, Chantal, De Reys, Mara, Greene, Daniel, Jenkins, Benjamin, Grassi, Luigi, Seyres, Denis, Burden, Frances, Whitehorn, Deborah, Shamardina, Olga, Papadia, Sofia, Gomez, Keith, BioResource, NIHR, Van Geet, Chris, Koulman, Albert, Ouwehand, Willem H., Ghevaert, Cedric, Frontini, Mattia, Turro, Ernest, Freson, Kathleen
Τόπος έκδοσης Haematologica (2019)

Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems

ανά Schuyler, Ronald P., Merkel, Angelika, Raineri, Emanuele, Altucci, Lucia, Vellenga, Edo, Martens, Joost H.A., Pourfarzad, Farzin, Kuijpers, Taco W., Burden, Frances, Farrow, Samantha, Downes, Kate, Ouwehand, Willem H., Clarke, Laura, Datta, Avik, Lowy, Ernesto, Flicek, Paul, Frontini, Mattia, Stunnenberg, Hendrik G., Martín-Subero, José I., Gut, Ivo, Heath, Simon
Τόπος έκδοσης Cell Rep (2016)

Chromosome contacts in activated T cells identify autoimmune disease candidate genes

ανά Burren, Oliver S., Rubio García, Arcadio, Javierre, Biola-Maria, Rainbow, Daniel B., Cairns, Jonathan, Cooper, Nicholas J., Lambourne, John J., Schofield, Ellen, Castro Dopico, Xaquin, Ferreira, Ricardo C., Coulson, Richard, Burden, Frances, Rowlston, Sophia P., Downes, Kate, Wingett, Steven W., Frontini, Mattia, Ouwehand, Willem H., Fraser, Peter, Spivakov, Mikhail, Todd, John A., Wicker, Linda S., Cutler, Antony J., Wallace, Chris
Τόπος έκδοσης Genome Biol (2017)

Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease

ανά Watt, Stephen, Vasquez, Louella, Walter, Klaudia, Mann, Alice L., Kundu, Kousik, Chen, Lu, Sims, Ying, Ecker, Simone, Burden, Frances, Farrow, Samantha, Farr, Ben, Iotchkova, Valentina, Elding, Heather, Mead, Daniel, Tardaguila, Manuel, Ponstingl, Hannes, Richardson, David, Datta, Avik, Flicek, Paul, Clarke, Laura, Downes, Kate, Pastinen, Tomi, Fraser, Peter, Frontini, Mattia, Javierre, Biola-Maria, Spivakov, Mikhail, Soranzo, Nicole
Τόπος έκδοσης Nat Commun (2021)

Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

ανά Javierre, Biola M., Burren, Oliver S., Wilder, Steven P., Kreuzhuber, Roman, Hill, Steven M., Sewitz, Sven, Cairns, Jonathan, Wingett, Steven W., Várnai, Csilla, Thiecke, Michiel J., Burden, Frances, Farrow, Samantha, Cutler, Antony J., Rehnström, Karola, Downes, Kate, Grassi, Luigi, Kostadima, Myrto, Freire-Pritchett, Paula, Wang, Fan, Stunnenberg, Hendrik G., Todd, John A., Zerbino, Daniel R., Stegle, Oliver, Ouwehand, Willem H., Frontini, Mattia, Wallace, Chris, Spivakov, Mikhail, Fraser, Peter
Τόπος έκδοσης Cell (2016)

Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity

ανά Saeed, Sadia, Quintin, Jessica, Kerstens, Hindrik H.D., Rao, Nagesha A, Aghajanirefah, Ali, Matarese, Filomena, Cheng, Shih-Chin, Ratter, Jacqueline, Berentsen, Kim, van der Ent, Martijn A., Sharifi, Nilofar, Janssen-Megens, Eva M., Huurne, Menno Ter, Mandoli, Amit, van Schaik, Tom, Ng, Aylwin, Burden, Frances, Downes, Kate, Frontini, Mattia, Kumar, Vinod, Giamarellos-Bourboulis, Evangelos J, Ouwehand, Willem H, van der Meer, Jos W.M., Joosten, Leo A.B., Wijmenga, Cisca, Martens, Joost H.A., Xavier, Ramnik J., Logie, Colin, Netea, Mihai G., Stunnenberg, Hendrik G.
Τόπος έκδοσης Science (2014)

Increased DNA methylation variability in type 1 diabetes across three immune effector cell types

ανά Paul, Dirk S., Teschendorff, Andrew E., Dang, Mary A.N., Lowe, Robert, Hawa, Mohammed I., Ecker, Simone, Beyan, Huriya, Cunningham, Stephanie, Fouts, Alexandra R., Ramelius, Anita, Burden, Frances, Farrow, Samantha, Rowlston, Sophia, Rehnstrom, Karola, Frontini, Mattia, Downes, Kate, Busche, Stephan, Cheung, Warren A., Ge, Bing, Simon, Marie-Michelle, Bujold, David, Kwan, Tony, Bourque, Guillaume, Datta, Avik, Lowy, Ernesto, Clarke, Laura, Flicek, Paul, Libertini, Emanuele, Heath, Simon, Gut, Marta, Gut, Ivo G, Ouwehand, Willem H., Pastinen, Tomi, Soranzo, Nicole, Hofer, Sabine E., Karges, Beate, Meissner, Thomas, Boehm, Bernhard O., Cilio, Corrado, Elding Larsson, Helena, Lernmark, Åke, Steck, Andrea K., Rakyan, Vardhman K., Beck, Stephan, Leslie, R. David
Τόπος έκδοσης Nat Commun (2016)

Platelet function is modified by common sequence variation in megakaryocyte super enhancers

ανά Petersen, Romina, Lambourne, John J., Javierre, Biola M., Grassi, Luigi, Kreuzhuber, Roman, Ruklisa, Dace, Rosa, Isabel M., Tomé, Ana R., Elding, Heather, van Geffen, Johanna P., Jiang, Tao, Farrow, Samantha, Cairns, Jonathan, Al-Subaie, Abeer M., Ashford, Sofie, Attwood, Antony, Batista, Joana, Bouman, Heleen, Burden, Frances, Choudry, Fizzah A., Clarke, Laura, Flicek, Paul, Garner, Stephen F., Haimel, Matthias, Kempster, Carly, Ladopoulos, Vasileios, Lenaerts, An-Sofie, Materek, Paulina M., McKinney, Harriet, Meacham, Stuart, Mead, Daniel, Nagy, Magdolna, Penkett, Christopher J., Rendon, Augusto, Seyres, Denis, Sun, Benjamin, Tuna, Salih, van der Weide, Marie-Elise, Wingett, Steven W., Martens, Joost H., Stegle, Oliver, Richardson, Sylvia, Vallier, Ludovic, Roberts, David J., Freson, Kathleen, Wernisch, Lorenz, Stunnenberg, Hendrik G., Danesh, John, Fraser, Peter, Soranzo, Nicole, Butterworth, Adam S., Heemskerk, Johan W., Turro, Ernest, Spivakov, Mikhail, Ouwehand, Willem H., Astle, William J., Downes, Kate, Kostadima, Myrto, Frontini, Mattia
Τόπος έκδοσης Nat Commun (2017)

Transcriptional diversity during lineage commitment of human blood progenitors

ανά Chen, Lu, Kostadima, Myrto, Martens, Joost H.A., Canu, Giovanni, Garcia, Sara P., Turro, Ernest, Downes, Kate, Macaulay, Iain C., Bielczyk-Maczynska, Ewa, Coe, Sophia, Farrow, Samantha, Poudel, Pawan, Burden, Frances, Jansen, Sjoert B.G., Astle, William J., Attwood, Antony, Bariana, Tadbir, de Bono, Bernard, Breschi, Alessandra, Chambers, John C., Consortium, BRIDGE, Choudry, Fizzah A., Clarke, Laura, Coupland, Paul, van der Ent, Martijn, Erber, Wendy N., Jansen, Joop H., Favier, Rémi, Fenech, Matthew E., Foad, Nicola, Freson, Kathleen, van Geet, Chris, Gomez, Keith, Guigo, Roderic, Hampshire, Daniel, Kelly, Anne M., Kerstens, Hindrik H.D., Kooner, Jaspal S., Laffan, Michael, Lentaigne, Claire, Labalette, Charlotte, Martin, Tiphaine, Meacham, Stuart, Mumford, Andrew, Nürnberg, Sylvia, Palumbo, Emilio, van der Reijden, Bert A., Richardson, David, Sammut, Stephen J., Slodkowicz, Greg, Tamuri, Asif U., Vasquez, Louella, Voss, Katrin, Watt, Stephen, Westbury, Sarah, Flicek, Paul, Loos, Remco, Goldman, Nick, Bertone, Paul, Read, Randy J., Richardson, Sylvia, Cvejic, Ana, Soranzo, Nicole, Ouwehand, Willem H., Stunnenberg, Hendrik G., Frontini, Mattia, Rendon, Augusto
Τόπος έκδοσης Science (2014)

Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome

ανά Sims, Matthew C., Mayer, Louisa, Collins, Janine H., Bariana, Tadbir K., Megy, Karyn, Lavenu-Bombled, Cecile, Seyres, Denis, Kollipara, Laxmikanth, Burden, Frances S., Greene, Daniel, Lee, Dave, Rodriguez-Romera, Antonio, Alessi, Marie-Christine, Astle, William J., Bahou, Wadie F., Bury, Loredana, Chalmers, Elizabeth, Da Silva, Rachael, De Candia, Erica, Deevi, Sri V. V., Farrow, Samantha, Gomez, Keith, Grassi, Luigi, Greinacher, Andreas, Gresele, Paolo, Hart, Dan, Hurtaud, Marie-Françoise, Kelly, Anne M., Kerr, Ron, Le Quellec, Sandra, Leblanc, Thierry, Leinøe, Eva B., Mapeta, Rutendo, McKinney, Harriet, Michelson, Alan D., Morais, Sara, Nugent, Diane, Papadia, Sofia, Park, Soo J., Pasi, John, Podda, Gian Marco, Poon, Man-Chiu, Reed, Rachel, Sekhar, Mallika, Shalev, Hanna, Sivapalaratnam, Suthesh, Steinberg-Shemer, Orna, Stephens, Jonathan C., Tait, Robert C., Turro, Ernest, Wu, John K. M., Zieger, Barbara, Kuijpers, Taco W., Whetton, Anthony D., Sickmann, Albert, Freson, Kathleen, Downes, Kate, Erber, Wendy N., Frontini, Mattia, Nurden, Paquita, Ouwehand, Willem H., Favier, Remi, Guerrero, Jose A.
Τόπος έκδοσης Blood (2020)

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells

ανά Chen, Lu, Ge, Bing, Casale, Francesco Paolo, Vasquez, Louella, Kwan, Tony, Garrido-Martín, Diego, Watt, Stephen, Yan, Ying, Kundu, Kousik, Ecker, Simone, Datta, Avik, Richardson, David, Burden, Frances, Mead, Daniel, Mann, Alice L., Fernandez, Jose Maria, Rowlston, Sophia, Wilder, Steven P., Farrow, Samantha, Shao, Xiaojian, Lambourne, John J., Redensek, Adriana, Albers, Cornelis A., Amstislavskiy, Vyacheslav, Ashford, Sofie, Berentsen, Kim, Bomba, Lorenzo, Bourque, Guillaume, Bujold, David, Busche, Stephan, Caron, Maxime, Chen, Shu-Huang, Cheung, Warren, Delaneau, Oliver, Dermitzakis, Emmanouil T., Elding, Heather, Colgiu, Irina, Bagger, Frederik O., Flicek, Paul, Habibi, Ehsan, Iotchkova, Valentina, Janssen-Megens, Eva, Kim, Bowon, Lehrach, Hans, Lowy, Ernesto, Mandoli, Amit, Matarese, Filomena, Maurano, Matthew T., Morris, John A., Pancaldi, Vera, Pourfarzad, Farzin, Rehnstrom, Karola, Rendon, Augusto, Risch, Thomas, Sharifi, Nilofar, Simon, Marie-Michelle, Sultan, Marc, Valencia, Alfonso, Walter, Klaudia, Wang, Shuang-Yin, Frontini, Mattia, Antonarakis, Stylianos E., Clarke, Laura, Yaspo, Marie-Laure, Beck, Stephan, Guigo, Roderic, Rico, Daniel, Martens, Joost H.A., Ouwehand, Willem H., Kuijpers, Taco W., Paul, Dirk S., Stunnenberg, Hendrik G., Stegle, Oliver, Downes, Kate, Pastinen, Tomi, Soranzo, Nicole
Τόπος έκδοσης Cell (2016)