Chromosome contacts in activated T cells identify autoimmune disease candidate genes

BACKGROUND: Autoimmune disease-associated variants are preferentially found in regulatory regions in immune cells, particularly CD4(+) T cells. Linking such regulatory regions to gene promoters in disease-relevant cell contexts facilitates identification of candidate disease genes. RESULTS: Within 4...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Burren, Oliver S., Rubio García, Arcadio, Javierre, Biola-Maria, Rainbow, Daniel B., Cairns, Jonathan, Cooper, Nicholas J., Lambourne, John J., Schofield, Ellen, Castro Dopico, Xaquin, Ferreira, Ricardo C., Coulson, Richard, Burden, Frances, Rowlston, Sophia P., Downes, Kate, Wingett, Steven W., Frontini, Mattia, Ouwehand, Willem H., Fraser, Peter, Spivakov, Mikhail, Todd, John A., Wicker, Linda S., Cutler, Antony J., Wallace, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584004/
https://ncbi.nlm.nih.gov/pubmed/28870212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1285-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados