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Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions

The three-dimensional organization of the genome is linked to its function. For example, regulatory elements such as transcriptional enhancers control the spatio-temporal expression of their target genes through physical contact, often bridging considerable (in some cases hundreds of kilobases) geno...

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Dettagli Bibliografici
Pubblicato in:J Vis Exp
Autori principali: Schoenfelder, Stefan, Javierre, Biola-Maria, Furlan-Magaril, Mayra, Wingett, Steven W., Fraser, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6102006/
https://ncbi.nlm.nih.gov/pubmed/30010637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57320
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