Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition

Transcriptional enhancers, including super-enhancers (SEs), form physical interactions with promoters to regulate cell-type-specific gene expression. SEs are characterized by high transcription factor occupancy and large domains of active chromatin, and they are commonly assigned to target promoters...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Novo, Clara Lopes, Javierre, Biola-Maria, Cairns, Jonathan, Segonds-Pichon, Anne, Wingett, Steven W., Freire-Pritchett, Paula, Furlan-Magaril, Mayra, Schoenfelder, Stefan, Fraser, Peter, Rugg-Gunn, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863031/
https://ncbi.nlm.nih.gov/pubmed/29514091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.040
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