Global Reorganization of the Nuclear Landscape in Senescent Cells

Cellular senescence has been implicated in tumor suppression, development, and aging and is accompanied by large-scale chromatin rearrangements, forming senescence-associated heterochromatic foci (SAHF). However, how the chromatin is reorganized during SAHF formation is poorly understood. Furthermor...

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Vydáno v:Cell Rep
Hlavní autoři: Chandra, Tamir, Ewels, Philip Andrew, Schoenfelder, Stefan, Furlan-Magaril, Mayra, Wingett, Steven William, Kirschner, Kristina, Thuret, Jean-Yves, Andrews, Simon, Fraser, Peter, Reik, Wolf
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542308/
https://ncbi.nlm.nih.gov/pubmed/25640177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.12.055
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