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Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity
INTRODUCTION: Monocytes circulate in the bloodstream for up to 3–5 days. Concomitantly, immunological imprinting of either tolerance (immunosuppression) or trained immunity (innate immune memory) determines the functional fate of monocytes and monocyte-derived macrophages, as observed after infectio...
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| Publié dans: | Science |
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4242194/ https://ncbi.nlm.nih.gov/pubmed/25258085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1251086 |
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