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Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity
INTRODUCTION: Monocytes circulate in the bloodstream for up to 3–5 days. Concomitantly, immunological imprinting of either tolerance (immunosuppression) or trained immunity (innate immune memory) determines the functional fate of monocytes and monocyte-derived macrophages, as observed after infectio...
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| Udgivet i: | Science |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4242194/ https://ncbi.nlm.nih.gov/pubmed/25258085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1251086 |
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