Decoding the DNA methylome of mantle cell lymphoma in the light of the entire B cell lineage

We analyzed the in silico purified DNA methylation signatures of 82 mantle cell lymphomas (MCL) in comparison with cell subpopulations spanning the entire B cell lineage. We identified two MCL subgroups, respectively carrying epigenetic imprints of germinal center-inexperienced and germinal center-e...

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Vydáno v:Cancer Cell
Hlavní autoři: Queirós, Ana C., Beekman, Renée, Vilarrasa-Blasi, Roser, Duran-Ferrer, Martí, Clot, Guillem, Merkel, Angelika, Raineri, Emanuele, Russiño, Nuria, Castellano, Giancarlo, Beà, Sílvia, Navarro, Alba, Kulis, Marta, Verdaguer-Dot, Núria, Jares, Pedro, Enjuanes, Anna, Calasanz, María José, Bergmann, Anke, Vater, Inga, Salaverría, Itziar, van de Werken, Harmen J. G., Wilson, Wyndham H., Datta, Avik, Flicek, Paul, Royo, Romina, Martens, Joost, Giné, Eva, Lopez-Guillermo, Armando, Stunnenberg, Hendrik G., Klapper, Wolfram, Pott, Christiane, Heath, Simon, Gut, Ivo G., Siebert, Reiner, Campo, Elías, Martín-Subero, José I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805090/
https://ncbi.nlm.nih.gov/pubmed/27846393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.09.014
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