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The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes

The precise regulation of S-phase–specific genes is critical for cell proliferation. How the repressive chromatin configuration mediated by the retinoblastoma protein and repressor E2F factors changes at the G1/S transition to allow transcription activation is unclear. Here we show ChIP-on-chip stud...

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Autors principals: Subtil-Rodríguez, Alicia, Vázquez-Chávez, Elena, Ceballos-Chávez, María, Rodríguez-Paredes, Manuel, Martín-Subero, José I., Esteller, Manel, Reyes, José C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936757/
https://ncbi.nlm.nih.gov/pubmed/24265227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1161
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