Rho family GTPases

Por Manser, Ed.
Publicado em 2005

The PAKs come of age: Celebrating 18 years of discovery

Por Field, Jeffrey, Manser, Ed
Publicado em 2012

Myotonic dystrophy kinase-related Cdc42-binding kinases (MRCK), the ROCK-like effectors of Cdc42 and Rac1

Por Zhao, Zhuoshen, Manser, Ed
Publicado no Small GTPases (2015)

PAK and other Rho-associated kinases – effectors with surprisingly diverse mechanisms of regulation

Por Zhao, Zhou-shen, Manser, Ed
Publicado em 2005

The RhoA GEF Syx Is a Target of Rnd3 and Regulated via a Raf1-Like Ubiquitin-Related Domain

Por Goh, Liuh Ling, Manser, Ed
Publicado em 2010

Do PAKs make good drug targets?

Por Zhao, Zhuo-shen, Manser, Ed
Publicado em 2010

The GTPase-deficient Rnd Proteins Are Stabilized by Their Effectors

Por Goh, Liuh Ling, Manser, Ed
Publicado em 2012

PAK family kinases: Physiological roles and regulation

Por Zhao, Zhuo-shen, Manser, Ed
Publicado em 2012

Arg Kinase-binding Protein 2 (ArgBP2) Interaction with α-Actinin and Actin Stress Fibers Inhibits Cell Migration

Por Anekal, Praju Vikas, Yong, Jeffery, Manser, Ed
Publicado no J Biol Chem (2015)

A Vertebrate-Specific Chp-PAK-PIX Pathway Maintains E-Cadherin at Adherens Junctions during Zebrafish Epiboly

Por Tay, Hwee Goon, Ng, Yuen Wai, Manser, Ed
Publicado em 2010

A Robust Protocol to Map Binding Sites of the 14-3-3 Interactome: Cdc25C Requires Phosphorylation of Both S216 and S263 to bind 14-3-3

Por Chan, Perry M., Ng, Yuen-Wai, Manser, Ed
Publicado em 2011

GIT1 Activates p21-Activated Kinase through a Mechanism Independent of p21 Binding

Por Loo, Tsui-Han, Ng, Yuen-Wai, Lim, Louis, Manser, Ed
Publicado em 2004

Cytoplasmic ACK1 Interaction with Multiple Receptor Tyrosine Kinases Is Mediated by Grb2: AN ANALYSIS OF ACK1 EFFECTS ON Axl SIGNALING

Por Pao-Chun, Lin, Chan, Perry M., Chan, Wing, Manser, Ed
Publicado em 2009

DAAM1 Is a Formin Required for Centrosome Re-Orientation during Cell Migration

Por Ang, Su-Fen, Zhao, Zhuo-shen, Lim, Louis, Manser, Ed
Publicado em 2010

Collapsin Response Mediator Proteins (CRMPs) Are a New Class of Microtubule-associated Protein (MAP) That Selectively Interacts with Assembled Microtubules via a Taxol-sensitive Bi...

Por Lin, Pao-Chun, Chan, Perry M., Hall, Christine, Manser, Ed
Publicado em 2011

The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity

Por Selamat, Widyawilis, Tay, Pei-Ling Felicia, Baskaran, Yohendran, Manser, Ed
Publicado no PLoS One (2015)

Regulation of IRSp53-Dependent Filopodial Dynamics by Antagonism between 14-3-3 Binding and SH3-Mediated Localization

Por Robens , Jeffrey M., Yeow-Fong, Lee, Ng, Elsa, Hall, Christine, Manser, Ed
Publicado em 2010

Group I and II mammalian PAKs have different modes of activation by Cdc42

Por Baskaran, Yohendran, Ng, Yuen-Wai, Selamat, Widyawilis, Ling, Felicia Tay Pei, Manser, Ed
Publicado em 2012

Formin DAAM1 Organizes Actin Filaments in the Cytoplasmic Nodal Actin Network

Por Luo, Weiwei, Lieu, Zi Zhao, Manser, Ed, Bershadsky, Alexander D., Sheetz, Michael P.
Publicado no PLoS One (2016)

Down-regulation of Active ACK1 Is Mediated by Association with the E3 Ubiquitin Ligase Nedd4-2

Por Chan, Wing, Tian, Rui, Lee, Yeow-Fong, Sit, Soon Tuck, Lim, Louis, Manser, Ed
Publicado em 2009