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The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity

The serine/threonine kinase PAK4 is a Cdc42 effector whose role is not well understood; overexpression of PAK4 has been associated with some cancers, and there are reports that correlate kinase level with increased cell migration in vitro. Here we report that PAK4 is primarily associated with cell-c...

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Pubblicato in:PLoS One
Autori principali: Selamat, Widyawilis, Tay, Pei-Ling Felicia, Baskaran, Yohendran, Manser, Ed
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466050/
https://ncbi.nlm.nih.gov/pubmed/26068882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129634
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