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The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity

The serine/threonine kinase PAK4 is a Cdc42 effector whose role is not well understood; overexpression of PAK4 has been associated with some cancers, and there are reports that correlate kinase level with increased cell migration in vitro. Here we report that PAK4 is primarily associated with cell-c...

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Udgivet i:PLoS One
Main Authors: Selamat, Widyawilis, Tay, Pei-Ling Felicia, Baskaran, Yohendran, Manser, Ed
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466050/
https://ncbi.nlm.nih.gov/pubmed/26068882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129634
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