Rho family GTPases

door Manser, Ed.
Gepubliceerd in 2005

The PAKs come of age: Celebrating 18 years of discovery

door Field, Jeffrey, Manser, Ed
Gepubliceerd in 2012

Myotonic dystrophy kinase-related Cdc42-binding kinases (MRCK), the ROCK-like effectors of Cdc42 and Rac1

door Zhao, Zhuoshen, Manser, Ed
Gepubliceerd in Small GTPases (2015)

PAK and other Rho-associated kinases – effectors with surprisingly diverse mechanisms of regulation

door Zhao, Zhou-shen, Manser, Ed
Gepubliceerd in 2005

The RhoA GEF Syx Is a Target of Rnd3 and Regulated via a Raf1-Like Ubiquitin-Related Domain

door Goh, Liuh Ling, Manser, Ed
Gepubliceerd in 2010

Do PAKs make good drug targets?

door Zhao, Zhuo-shen, Manser, Ed
Gepubliceerd in 2010

The GTPase-deficient Rnd Proteins Are Stabilized by Their Effectors

door Goh, Liuh Ling, Manser, Ed
Gepubliceerd in 2012

PAK family kinases: Physiological roles and regulation

door Zhao, Zhuo-shen, Manser, Ed
Gepubliceerd in 2012

Arg Kinase-binding Protein 2 (ArgBP2) Interaction with α-Actinin and Actin Stress Fibers Inhibits Cell Migration

door Anekal, Praju Vikas, Yong, Jeffery, Manser, Ed
Gepubliceerd in J Biol Chem (2015)

A Vertebrate-Specific Chp-PAK-PIX Pathway Maintains E-Cadherin at Adherens Junctions during Zebrafish Epiboly

door Tay, Hwee Goon, Ng, Yuen Wai, Manser, Ed
Gepubliceerd in 2010

A Robust Protocol to Map Binding Sites of the 14-3-3 Interactome: Cdc25C Requires Phosphorylation of Both S216 and S263 to bind 14-3-3

door Chan, Perry M., Ng, Yuen-Wai, Manser, Ed
Gepubliceerd in 2011

GIT1 Activates p21-Activated Kinase through a Mechanism Independent of p21 Binding

door Loo, Tsui-Han, Ng, Yuen-Wai, Lim, Louis, Manser, Ed
Gepubliceerd in 2004

Cytoplasmic ACK1 Interaction with Multiple Receptor Tyrosine Kinases Is Mediated by Grb2: AN ANALYSIS OF ACK1 EFFECTS ON Axl SIGNALING

door Pao-Chun, Lin, Chan, Perry M., Chan, Wing, Manser, Ed
Gepubliceerd in 2009

DAAM1 Is a Formin Required for Centrosome Re-Orientation during Cell Migration

door Ang, Su-Fen, Zhao, Zhuo-shen, Lim, Louis, Manser, Ed
Gepubliceerd in 2010

Collapsin Response Mediator Proteins (CRMPs) Are a New Class of Microtubule-associated Protein (MAP) That Selectively Interacts with Assembled Microtubules via a Taxol-sensitive Bi...

door Lin, Pao-Chun, Chan, Perry M., Hall, Christine, Manser, Ed
Gepubliceerd in 2011

The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity

door Selamat, Widyawilis, Tay, Pei-Ling Felicia, Baskaran, Yohendran, Manser, Ed
Gepubliceerd in PLoS One (2015)

Regulation of IRSp53-Dependent Filopodial Dynamics by Antagonism between 14-3-3 Binding and SH3-Mediated Localization

door Robens , Jeffrey M., Yeow-Fong, Lee, Ng, Elsa, Hall, Christine, Manser, Ed
Gepubliceerd in 2010

Group I and II mammalian PAKs have different modes of activation by Cdc42

door Baskaran, Yohendran, Ng, Yuen-Wai, Selamat, Widyawilis, Ling, Felicia Tay Pei, Manser, Ed
Gepubliceerd in 2012

Formin DAAM1 Organizes Actin Filaments in the Cytoplasmic Nodal Actin Network

door Luo, Weiwei, Lieu, Zi Zhao, Manser, Ed, Bershadsky, Alexander D., Sheetz, Michael P.
Gepubliceerd in PLoS One (2016)

Down-regulation of Active ACK1 Is Mediated by Association with the E3 Ubiquitin Ligase Nedd4-2

door Chan, Wing, Tian, Rui, Lee, Yeow-Fong, Sit, Soon Tuck, Lim, Louis, Manser, Ed
Gepubliceerd in 2009