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Arg Kinase-binding Protein 2 (ArgBP2) Interaction with α-Actinin and Actin Stress Fibers Inhibits Cell Migration

Cell migration requires dynamic remodeling of the actomyosin network. We report here that an adapter protein, ArgBP2, is a component of α-actinin containing stress fibers and inhibits migration. ArgBP2 is undetectable in many commonly studied cancer-derived cell lines. COS-7 and HeLa cells express A...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Anekal, Praju Vikas, Yong, Jeffery, Manser, Ed
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303664/
https://ncbi.nlm.nih.gov/pubmed/25429109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.610725
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