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CDC42 binds PAK4 via an extended GTPase-effector interface
The p21-activated kinase (PAK) group of serine/threonine kinases are downstream effectors of RHO GTPases and play important roles in regulation of the actin cytoskeleton, cell growth, survival, polarity, and development. Here we probe the interaction of the type II PAK, PAK4, with RHO GTPases. Using...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5776996/ https://ncbi.nlm.nih.gov/pubmed/29295922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717437115 |
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