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Mechanism and Rate Constants of the Cdc42 GTPase Binding with Intrinsically Disordered Effectors

Intrinsically disordered proteins (IDPs) are often involved in signaling and regulatory functions, through binding to cellular targets. Many IDPs undergo disorder-to-order transitions upon binding. Both the binding mechanisms and the magnitudes of the binding rate constants can have functional impor...

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Dades bibliogràfiques
Publicat a:Proteins
Autors principals: Pang, Xiaodong, Zhou, Huan-Xiang
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840055/
https://ncbi.nlm.nih.gov/pubmed/26879470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25018
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