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Mechanism and Rate Constants of the Cdc42 GTPase Binding with Intrinsically Disordered Effectors

Intrinsically disordered proteins (IDPs) are often involved in signaling and regulatory functions, through binding to cellular targets. Many IDPs undergo disorder-to-order transitions upon binding. Both the binding mechanisms and the magnitudes of the binding rate constants can have functional impor...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Pang, Xiaodong, Zhou, Huan-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840055/
https://ncbi.nlm.nih.gov/pubmed/26879470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25018
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