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Rate constants and mechanisms of intrinsically disordered proteins binding to structured targets

The binding of intrinsically disordered proteins (IDPs) to structured targets is gaining increasing attention. Here we review experimental and computational studies on the binding kinetics of IDPs. Experiments have yielded both the binding rate constants and the binding mechanisms, the latter via mu...

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Bibliografische gegevens
Hoofdauteurs: Zhou, Huan-Xiang, Pang, Xiaodong, Lu, Cai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402904/
https://ncbi.nlm.nih.gov/pubmed/22744607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cp41196b
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