Lenalidomide as a disease-modifying agent in patients with del(5q) myelodysplastic syndromes: linking mechanism of action to clinical outcomes

ανά Giagounidis, Aristoteles, Mufti, Ghulam J., Fenaux, Pierre, Germing, Ulrich, List, Alan, MacBeth, Kyle J.
Έκδοση 2013

Azacitidine and decitabine have different mechanisms of action in non-small cell lung cancer cell lines

ανά Nguyen, Aaron N, Hollenbach, Paul W, Richard, Normand, Luna-Moran, Antonio, Brady, Helen, Heise, Carla, MacBeth, Kyle J
Τόπος έκδοσης Lung Cancer (Auckl) (2010)

Pharmacokinetics and Pharmacodynamics with Extended Dosing of CC-486 in Patients with Hematologic Malignancies

ανά Laille, Eric, Shi, Tao, Garcia-Manero, Guillermo, Cogle, Christopher R., Gore, Steven D., Hetzer, Joel, Kumar, Keshava, Skikne, Barry, MacBeth, Kyle J.
Τόπος έκδοσης PLoS One (2015)

Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome

ανά Leung, Kevin K., Nguyen, Aaron, Shi, Tao, Tang, Lin, Ni, Xiaochun, Escoubet, Laure, MacBeth, Kyle J., DiMartino, Jorge, Wells, James A.
Τόπος έκδοσης Proc Natl Acad Sci U S A (2019)

A Comparison of Azacitidine and Decitabine Activities in Acute Myeloid Leukemia Cell Lines

ανά Hollenbach, Paul W., Nguyen, Aaron N., Brady, Helen, Williams, Michelle, Ning, Yuhong, Richard, Normand, Krushel, Leslie, Aukerman, Sharon L., Heise, Carla, MacBeth, Kyle J.
Έκδοση 2010

Phase I Study of Oral Azacitidine in Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, and Acute Myeloid Leukemia

ανά Garcia-Manero, Guillermo, Gore, Steven D., Cogle, Christopher, Ward, Renee, Shi, Tao, MacBeth, Kyle J., Laille, Eric, Giordano, Heidi, Sakoian, Sarah, Jabbour, Elias, Kantarjian, Hagop, Skikne, Barry
Έκδοση 2011

Impact of somatic mutations on response to lenalidomide in lower-risk non-del(5q) myelodysplastic syndromes patients

ανά Santini, Valeria, Fenaux, Pierre, Giagounidis, Aristoteles, Platzbecker, Uwe, List, Alan F., Haferlach, Torsten, Zhong, Jim, Wu, Chengqing, Mavrommatis, Konstantinos, Beach, C. L., MacBeth, Kyle J., Almeida, Antonio
Τόπος έκδοσης Leukemia (2020)

Transcriptional Responses to Estrogen and Progesterone in Mammary Gland Identify Networks Regulating p53 Activity

ανά Lu, Shaolei, Becker, Klaus A., Hagen, Mary J., Yan, Haoheng, Roberts, Amy L., Mathews, Lesley A., Schneider, Sallie S., Siegelmann, Hava T., MacBeth, Kyle J., Tirrell, Stephen M., Blanchard, Jeffrey L., Jerry, D. Joseph
Έκδοση 2008

p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q)

ανά Saft, Leonie, Karimi, Mohsen, Ghaderi, Mehran, Matolcsy, András, Mufti, Ghulam J., Kulasekararaj, Austin, Göhring, Gudrun, Giagounidis, Aristoteles, Selleslag, Dominik, Muus, Petra, Sanz, Guillermo, Mittelman, Moshe, Bowen, David, Porwit, Anna, Fu, Tommy, Backstrom, Jay, Fenaux, Pierre, MacBeth, Kyle J., Hellström-Lindberg, Eva
Έκδοση 2014

Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care

ανά Döhner, Hartmut, Dolnik, Anna, Tang, Lin, Seymour, John F., Minden, Mark D., Stone, Richard M., del Castillo, Teresa Bernal, Al-Ali, Haifa Kathrin, Santini, Valeria, Vyas, Paresh, Beach, C. L., MacBeth, Kyle J., Skikne, Barry S., Songer, Steve, Tu, Nora, Bullinger, Lars, Dombret, Hervé
Τόπος έκδοσης Leukemia (2018)

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS

ανά Krönke, Jan, Fink, Emma C., Hollenbach, Paul W., MacBeth, Kyle J., Hurst, Slater N., Udeshi, Namrata D., Chamberlain, Philip P., Mani, D.R., Man, Hon Wah, Gandhi, Anita K., Svinkina, Tanya, Schneider, Rebekka K., McConkey, Marie, Järås, Marcus, Griffiths, Elizabeth, Wetzler, Meir, Bullinger, Lars, Cathers, Brian E., Carr, Steven A., Chopra, Rajesh, Ebert, Benjamin L.
Τόπος έκδοσης Nature (2015)

TP53 mutations in myelodysplastic syndromes and secondary AML confer an immunosuppressive phenotype

ανά Sallman, David A., McLemore, Amy F., Aldrich, Amy L., Komrokji, Rami S., McGraw, Kathy L., Dhawan, Abhishek, Geyer, Susan, Hou, Hsin-An, Eksioglu, Erika A., Sullivan, Amy, Warren, Sarah, MacBeth, Kyle J., Meggendorfer, Manja, Haferlach, Torsten, Boettcher, Steffen, Ebert, Benjamin L., Al Ali, Najla H., Lancet, Jeffrey E., Cleveland, John L., Padron, Eric, List, Alan F.
Τόπος έκδοσης Blood (2020)

Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia

ανά Wang, Feng, Morita, Kiyomi, DiNardo, Courtney D., Furudate, Ken, Tanaka, Tomoyuki, Yan, Yuanqing, Patel, Keyur P., MacBeth, Kyle J., Wu, Bin, Liu, Guowen, Frattini, Mark, Matthews, Jairo A., Little, Latasha D., Gumbs, Curtis, Song, Xingzhi, Zhang, Jianhua, Thompson, Erika J., Kadia, Tapan M., Garcia-Manero, Guillermo, Jabbour, Elias, Ravandi, Farhad, Bhalla, Kapil N., Konopleva, Marina, Kantarjian, Hagop M., Andrew Futreal, P., Takahashi, Koichi
Τόπος έκδοσης Nat Commun (2021)

Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib

ανά Stein, Eytan M., DiNardo, Courtney D., Fathi, Amir T., Pollyea, Daniel A., Stone, Richard M., Altman, Jessica K., Roboz, Gail J., Patel, Manish R., Collins, Robert, Flinn, Ian W., Sekeres, Mikkael A., Stein, Anthony S., Kantarjian, Hagop M., Levine, Ross L., Vyas, Paresh, MacBeth, Kyle J., Tosolini, Alessandra, VanOostendorp, Jason, Xu, Qiang, Gupta, Ira, Lila, Thomas, Risueno, Alberto, Yen, Katharine E., Wu, Bin, Attar, Eyal C., Tallman, Martin S., de Botton, Stéphane
Τόπος έκδοσης Blood (2019)

Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition

ανά Harding, James J., Lowery, Maeve A., Shih, Alan H., Schvartzman, Juan M., Hou, Shengqi, Famulare, Christopher, Patel, Minal, Roshal, Mikhail, Do, Richard K., Zehir, Ahmet, You, Daoqi, Selcuklu, S. Duygu, Viale, Agnes, Tallman, Martin S., Hyman, David M., Reznik, Ed, Finley, Lydia W.S., Papaemmanuil, Elli, Tosolini, Alessandra, Frattini, Mark G., MacBeth, Kyle J., Liu, Guowen, Fan, Bin, Choe, Sung, Wu, Bin, Janjigian, Yelena Y., Mellinghoff, Ingo K., Diaz, Luis A., Levine, Ross L., Abou-Alfa, Ghassan K., Stein, Eytan M., Intlekofer, Andrew M.
Τόπος έκδοσης Cancer Discov (2018)