Antitumor mechanisms when pRb and p53 are genetically inactivated

Por Zhu, Liang, Lu, Zhonglei, Zhao, Hongling
Publicado no Oncogene (2014)

Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis

Por Zhao, Hongling, Wang, Hongbo, Bauzon, Frederick, Lu, Zhonglei, Fu, Hao, Cui, Jinhua, Zhu, Liang
Publicado no J Biol Chem (2016)

p27T187A knockin identifies Skp2/Cks1 pocket inhibitors for advanced prostate cancer

Por Zhao, Hongling, Lu, Zhonglei, Bauzon, Frederick, Fu, Hao, Cui, Jinhua, Locker, Joseph, Zhu, Liang
Publicado no Oncogene (2016)

Skp2 suppresses apoptosis in Rb1 deficient tumors by limiting E2F1 activity

Por Lu, Zhonglei, Bauzon, Frederick, Fu, Hao, Cui, Jinhua, Zhao, Hongling, Nakayama, Keiko, Nakayama, Keiich I., Zhu, Liang
Publicado em 2014

Para-Aminobenzoic Acid (PABA) Synthase Enhances Thermotolerance of Mushroom Agaricus bisporus

Por Lu, Zhonglei, Kong, Xiangxiang, Lu, Zhaoming, Xiao, Meixiang, Chen, Meiyuan, Zhu, Liang, Shen, Yuemao, Hu, Xiangyang, Song, Siyang
Publicado em 2014

Skp2 deletion unmasks a p27 safeguard that blocks tumorigenesis in the absence of pRb and p53 tumor suppressors

Por Zhao, Hongling, Bauzon, Frederick, Fu, Hao, Lu, Zhonglei, Cui, Jinhua, Nakayama, Keiko, Nakayama, Keiich I., Locker, Joseph, Zhu, Liang
Publicado em 2013

Substituting Threonine 187 with Alanine in p27Kip1 Prevents Pituitary Tumorigenesis by Two-Hit Loss of Rb1 and Enhances Humoral Immunity in Old Age

Por Zhao, Hongling, Bauzon, Frederick, Bi, Enguang, Yu, J. Jessica, Fu, Hao, Lu, Zhonglei, Cui, Jinhua, Jeon, Hyungjun, Zang, Xingxing, Ye, B. Hilda, Zhu, Liang
Publicado no J Biol Chem (2015)

Experimental Model for Successful Liver Cell Therapy by Lenti TTR-YapERT2 Transduced Hepatocytes with Tamoxifen Control of Yap Subcellular Location

Por Yovchev, Mladen, Jaber, Fadi L., Lu, Zhonglei, Patel, Shachi, Locker, Joseph, Rogler, Leslie E., Murray, John W., Sudol, Marius, Dabeva, Mariana D., Zhu, Liang, Shafritz, David A.
Publicado no Sci Rep (2016)

pRb is an obesity suppressor in hypothalamus and high-fat diet inhibits pRb in this location

Por Lu, Zhonglei, Marcelin, Genevieve, Bauzon, Frederick, Wang, Hongbo, Fu, Hao, Dun, Siok Le, Zhao, Hongling, Li, Xiaosong, Jo, Young-Hwan, Wardlaw, Sharon, Dun, Nae, Chua, Streamson, Zhu, Liang
Publicado em 2013