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pRb is an obesity suppressor in hypothalamus and high-fat diet inhibits pRb in this location
pRb is frequently inactivated in tumours by mutations or phosphorylation. Here, we investigated whether pRb plays a role in obesity. The Arcuate nucleus (ARC) in hypothalamus contains antagonizing POMC and AGRP/NPY neurons for negative and positive energy balance, respectively. Various aspects of AR...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
European Molecular Biology Organization
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604720/ https://ncbi.nlm.nih.gov/pubmed/23403926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.25 |
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