p107 is a suppressor of retinoblastoma development in pRb-deficient mice

Hemizygosity for the retinoblastoma gene RB in man strongly predisposes to retinoblastoma. In the mouse, however, Rb hemizygosity leaves the retina normal, whereas in Rb(−/−) chimeras pRb-deficient retinoblasts undergo apoptosis. To test whether concomitant inactivation of the Rb-related gene p107 i...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Robanus-Maandag, Els, Dekker, Marleen, van der Valk, Martin, Carrozza, Maria-Luisa, Jeanny, Jean-Claude, Dannenberg, Jan-Hermen, Berns, Anton, te Riele, Hein
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1998
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC316874/
https://ncbi.nlm.nih.gov/pubmed/9620848
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares