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Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb
In cycling cells, the retinoblastoma protein (pRb) is un- and/or hypo-phosphorylated in early G(1) and becomes hyper-phosphorylated in late G(1). The role of hypo-phosphorylation and identity of the relevant kinase(s) remains unknown. We show here that hypo-phosphorylated pRb associates with E2F in...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences of the USA
1997
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23451/ https://ncbi.nlm.nih.gov/pubmed/9380698 |
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