Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.

Alterations of various components of the cell cycle regulatory machinery that controls the progression of cells from a quiescent to a growing state contribute to the development of many human cancers. Such alterations include the deregulated expression of G1 cyclins, the loss of function of activiti...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Khleif, S N, DeGregori, J, Yee, C L, Otterson, G A, Kaye, F J, Nevins, J R, Howley, P M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39540/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8633069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.9.4350
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!