Codice QR

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

Hemizygosity for the retinoblastoma gene RB in man strongly predisposes to retinoblastoma. In the mouse, however, Rb hemizygosity leaves the retina normal, whereas in Rb(−/−) chimeras pRb-deficient retinoblasts undergo apoptosis. To test whether concomitant inactivation of the Rb-related gene p107 i...

Descrizione completa

Salvato in:
Pubblicato in:Genes Dev
Autori principali: Robanus-Maandag, Els, Dekker, Marleen, van der Valk, Martin, Carrozza, Maria-Luisa, Jeanny, Jean-Claude, Dannenberg, Jan-Hermen, Berns, Anton, te Riele, Hein
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1998
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316874/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9620848/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.11.1599
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!

Documenti analoghi