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pRB, a Tumor Suppressor with a Stabilizing Presence

The product of the retinoblastoma tumor susceptibility gene (RB1) is a key regulator of cell proliferation and this function is thought to be central to its tumor suppressive activity. Several studies have demonstrated that inactivation of pRB not only allows inappropriate proliferation, but also un...

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Detalhes bibliográficos
Main Authors: Manning, Amity L, Dyson, Nicholas J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149724/
https://ncbi.nlm.nih.gov/pubmed/21664133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2011.05.003
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