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pRB, a Tumor Suppressor with a Stabilizing Presence

The product of the retinoblastoma tumor susceptibility gene (RB1) is a key regulator of cell proliferation and this function is thought to be central to its tumor suppressive activity. Several studies have demonstrated that inactivation of pRB not only allows inappropriate proliferation, but also un...

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Bibliografiske detaljer
Main Authors: Manning, Amity L, Dyson, Nicholas J
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149724/
https://ncbi.nlm.nih.gov/pubmed/21664133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2011.05.003
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