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pRB, a Tumor Suppressor with a Stabilizing Presence

The product of the retinoblastoma tumor susceptibility gene (RB1) is a key regulator of cell proliferation and this function is thought to be central to its tumor suppressive activity. Several studies have demonstrated that inactivation of pRB not only allows inappropriate proliferation, but also un...

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Библиографические подробности
Главные авторы: Manning, Amity L, Dyson, Nicholas J
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149724/
https://ncbi.nlm.nih.gov/pubmed/21664133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2011.05.003
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