A kinase shRNA screen links LATS2 and the pRB tumor suppressor

pRB-mediated inhibition of cell proliferation is a complex process that depends on the action of many proteins. However, little is known about the specific pathways that cooperate with the Retinoblastoma protein (pRB) and the variables that influence pRB's ability to arrest tumor cells. Here we...

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Bibliografiske detaljer
Main Authors: Tschöp, Katrin, Conery, Andrew R., Litovchick, Larisa, DeCaprio, James A., Settleman, Jeffrey, Harlow, Ed, Dyson, Nicholas
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2011
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078707/
https://ncbi.nlm.nih.gov/pubmed/21498571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2000211
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