Maximizing the return on taxpayers' investments in fundamental biomedical research

Por Lorsch, Jon R.
Publicado no Mol Biol Cell (2015)

Should I Stay or Should I Go? Eukaryotic Translation Initiation Factors 1 and 1A Control Start Codon Recognition

Por Mitchell, Sarah F., Lorsch, Jon R.
Publicado em 2008

Eukaryotic Initiator tRNA: Finely Tuned and Ready for Action

Por Kolitz, Sarah E., Lorsch, Jon R.
Publicado em 2010

Molecular View of 43 S Complex Formation and Start Site Selection in Eukaryotic Translation Initiation

Por Lorsch, Jon R., Dever, Thomas E.
Publicado em 2010

The Mechanism of Eukaryotic Translation Initiation: New Insights and Challenges

Por Hinnebusch, Alan G., Lorsch, Jon R.
Publicado em 2012

Fixing problems with cell lines: Technologies and policies can improve authentication

Por Lorsch, Jon R., Collins, Francis S., Lippincott-Schwartz, Jennifer
Publicado no Science (2014)

Yeast initiator tRNA identity elements cooperate to influence multiple steps of translation initiation

Por Kapp, Lee D., Kolitz, Sarah E., Lorsch, Jon R.
Publicado em 2006

Kinetic and thermodynamic analysis of the role of start codon/anticodon base pairing during eukaryotic translation initiation

Por Kolitz, Sarah E., Takacs, Julie E., Lorsch, Jon R.
Publicado em 2009

Regulatory elements in eIF1A control the fidelity of start codon selection by modulating tRNA(i)(Met) binding to the ribosome

Por Saini, Adesh K., Nanda, Jagpreet S., Lorsch, Jon R., Hinnebusch, Alan G.
Publicado em 2010

Specific Domains in Yeast Translation Initiation Factor eIF4G Strongly Bias RNA Unwinding Activity of the eIF4F Complex toward Duplexes with 5′-Overhangs

Por Rajagopal, Vaishnavi, Park, Eun-Hee, Hinnebusch, Alan G., Lorsch, Jon R.
Publicado em 2012

Regulatory elements in eIF1A control the fidelity of start codon selection by modulating tRNAi(Met) binding to the ribosome

Por Saini, Adesh K., Nanda, Jagpreet S., Lorsch, Jon R., Hinnebusch, Alan G.
Publicado em 2013

Coordinated Movements of Eukaryotic Translation Initiation Factors eIF1, eIF1A, and eIF5 Trigger Phosphate Release from eIF2 in Response to Start Codon Recognition by the Ribosomal...

Por Nanda, Jagpreet S., Saini, Adesh K., Muñoz, Antonio M., Hinnebusch, Alan G., Lorsch, Jon R.
Publicado em 2013

Identification and Characterization of Functionally Critical, Conserved Motifs in the Internal Repeats and N-terminal Domain of Yeast Translation Initiation Factor 4B (yeIF4B)

Por Zhou, Fujun, Walker, Sarah E., Mitchell, Sarah F., Lorsch, Jon R., Hinnebusch, Alan G.
Publicado em 2014

Identification and characterization of functionally critical, conserved motifs in the internal repeats and N-terminal domain of yeast translation initiation factor 4B (yeIF4B).

Por Zhou, Fujun, Walker, Sarah E., Mitchell, Sarah F., Lorsch, Jon R., Hinnebusch, Alan G.
Publicado em 2014

Coupled Release of Eukaryotic Translation Initiation Factors 5B and 1A from 80S Ribosomes following Subunit Joining

Por Fringer, Jeanne M., Acker, Michael G., Fekete, Christie A., Lorsch, Jon R., Dever, Thomas E.
Publicado em 2007

Ribosome recycling step in yeast cytoplasmic protein synthesis is catalyzed by eEF3 and ATP

Por Kurata, Shinya, Nielsen, Klaus H., Mitchell, Sarah F., Lorsch, Jon R., Kaji, Akira, Kaji, Hideko
Publicado em 2010

Active yeast ribosome preparation using monolithic anion exchange chromatography

Por Munoz, Antonio M., Yourik, Paul, Rajagopal, Vaishnavi, Nanda, Jagpreet S., Lorsch, Jon R., Walker, Sarah E.
Publicado no RNA Biol (2016)

Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity

Por Yourik, Paul, Aitken, Colin Echeverría, Zhou, Fujun, Gupta, Neha, Hinnebusch, Alan G, Lorsch, Jon R
Publicado no eLife (2017)

Inhibition of protein synthesis by aminoglycoside-arginine conjugates.

Por Carriere, Marjolaine, Vijayabaskar, Veerappan, Applefield, Drew, Harvey, Isabelle, Garneau, Philippe, Lorsch, Jon, Lapidot, Aviva, Pelletier, Jerry
Publicado em 2002

β-Hairpin Loop of Eukaryotic Initiation Factor 1 (eIF1) Mediates 40 S Ribosome Binding to Regulate Initiator tRNA(Met) Recruitment and Accuracy of AUG Selection in Vivo

Por Martin-Marcos, Pilar, Nanda, Jagpreet, Luna, Rafael E., Wagner, Gerhard, Lorsch, Jon R., Hinnebusch, Alan G.
Publicado em 2013