β-Hairpin Loop of Eukaryotic Initiation Factor 1 (eIF1) Mediates 40 S Ribosome Binding to Regulate Initiator tRNA(Met) Recruitment and Accuracy of AUG Selection in Vivo

Recognition of the translation initiation codon is thought to require dissociation of eIF1 from the 40 S ribosomal subunit, enabling irreversible GTP hydrolysis (P(i) release) by the eIF2·GTP·Met-tRNA(i) ternary complex (TC), rearrangement of the 40 S subunit to a closed conformation incompatible wi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Martin-Marcos, Pilar, Nanda, Jagpreet, Luna, Rafael E., Wagner, Gerhard, Lorsch, Jon R., Hinnebusch, Alan G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779751/
https://ncbi.nlm.nih.gov/pubmed/23893413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.498642
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados