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Kinetic and thermodynamic analysis of the role of start codon/anticodon base pairing during eukaryotic translation initiation
Start codon recognition is a crucial event in the initiation of protein synthesis. To gain insight into the mechanism of start codon recognition in eukaryotes, we used a yeast reconstituted initiation system to isolate the step of Met-tRNA(i)•eIF2•GTP ternary complex (TC) binding to the 40S subunit....
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612769/ https://ncbi.nlm.nih.gov/pubmed/19029312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1318509 |
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