Neuronal Release of Cytokine IL-3 Triggered by Mechanosensitive Autostimulation of the P2X7 Receptor Is Neuroprotective

di Lim, Jason C., Lu, Wennan, Beckel, Jonathan M., Mitchell, Claire H.
Pubblicato in Front Cell Neurosci (2016)

Effects of Lidocaine and Articaine on Neuronal Survival and Recovery

di Albalawi, Farraj, Lim, Jason C., DiRenzo, Kyle V., Hersh, Elliot V., Mitchell, Claire H.
Pubblicato in Anesth Prog (2018)

The P2X7 receptor links mechanical strain to cytokine IL-6 upregulation and release in neurons and astrocytes

di Lu, Wennan, Albalawi, Farraj, Beckel, Jonathan M., Lim, Jason C., Laties, Alan M., Mitchell, Claire H.
Pubblicato in J Neurochem (2017)

The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain

di Albalawi, Farraj, Lu, Wennan, Beckel, Jonathan M., Lim, Jason C., McCaughey, Stuart A., Mitchell, Claire H.
Pubblicato in Front Cell Neurosci (2017)

Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X(7) receptors

di Xia, Jingsheng, Lim, Jason C, Lu, Wennan, Beckel, Jonathan M, Macarak, Edward J, Laties, Alan M, Mitchell, Claire H
Pubblicazione 2012

Approaches for detecting lysosomal alkalinization and impaired degradation in fresh and cultured RPE cells: evidence for a role in retinal degenerations

di Guha, Sonia, Coffey, Erin E., Lu, Wennan, Lim, Jason C., Beckel, Jonathan M., Laties, Alan M., Boesze-Battaglia, Kathleen, Mitchell, Claire H.
Pubblicazione 2014

Sequential Platelet-Derived Growth Factor–Simvastatin Release Promotes Dentoalveolar Regeneration

di Chang, Po-Chun, Chong, Li Yen, Dovban, Alex S.M., Lim, Lum Peng, Lim, Jason C., Kuo, Mark Yen-Ping, Wang, Chi-Hwa
Pubblicazione 2014

Independent Effects of γ-Aminobutyric Acid Transaminase (GABAT) on Metabolic and Sleep Homeostasis

di Maguire, Sarah E., Rhoades, Seth, Chen, Wen-Feng, Sengupta, Arjun, Yue, Zhifeng, Lim, Jason C., Mitchell, Claire H., Weljie, Aalim M., Sehgal, Amita
Pubblicato in J Biol Chem (2015)

Stimulation of TLR3 triggers release of lysosomal ATP in astrocytes and epithelial cells that requires TRPML1 channels

di Beckel, Jonathan M., Gómez, Néstor Más, Lu, Wennan, Campagno, Keith E., Nabet, Bardia, Albalawi, Farraj, Lim, Jason C., Boesze-Battaglia, Kathleen, Mitchell, Claire H.
Pubblicato in Sci Rep (2018)

Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris

di Guha, Sonia, Baltazar, Gabriel C., Tu, Leigh-Anne, Liu, Ji, Lim, Jason C., Lu, Wennan, Argall, Arthur, Boesze-Battaglia, Kathleen, Laties, Alan M., Mitchell, Claire H.
Pubblicazione 2012

Robust lysosomal calcium signaling through channel TRPML1 is impaired by lysosomal lipid accumulation

di Gómez, Néstor Más, Lu, Wennan, Lim, Jason C., Kiselyov, Kirill, Campagno, Keith E., Grishchuk, Yulia, Slaugenhaupt, Susan A., Pfeffer, Bruce A., Fliesler, Steven J., Mitchell, Claire H.
Pubblicato in FASEB J (2018)

TNFα Contributes to Diabetes Impaired Angiogenesis in Fracture Healing

di Lim, Jason C., Ko, Kang I., Mattos, Marcelo, Fang, Miao, Zhang, Citong, Feinberg, Daniel, Sindi, Hisham, Li, Shuai, Alblowi, Jazia, Kayal, Rayyan A., Einhorn, Thomas A., Gerstenfeld, Louis, Graves, Dana
Pubblicato in Bone (2017)

Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor

di Guha, Sonia, Baltazar, Gabriel C., Coffey, Erin E., Tu, Leigh-Anne, Lim, Jason C., Beckel, Jonathan M., Patel, Shaun, Eysteinsson, Thor, Lu, Wennan, O'Brien-Jenkins, Ann, Laties, Alan M., Mitchell, Claire H.
Pubblicazione 2013

The P2Y(12) Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4(-/-) Mouse Model of Retinal Degeneration

di Lu, Wennan, Gómez, Néstor M., Lim, Jason C., Guha, Sonia, O’Brien-Jenkins, Ann, Coffey, Erin E., Campagno, Keith E., McCaughey, Stuart A., Laties, Alan M., Carlsson, Leif G., Mitchell, Claire H.
Pubblicato in Front Pharmacol (2018)

Mechanosensitive release of ATP through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: a mechanism for purinergic involvem...

di Beckel, Jonathan M., Argall, Arthur J., Lim, Jason C., Xia, Jingsheng, Lu, Wennan, Coffey, Erin E., Macarak, Edward J., Shahidullah, Mohammed, Delamere, Nicholas A., Zode, Gulab S., Sheffield, Val C., Shestopalov, Valery I., Laties, Alan M., Mitchell, Claire H.
Pubblicazione 2014

CALHM3 is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes

di Ma, Zhongming, Taruno, Akiyuki, Ohmoto, Makoto, Jyotaki, Masafumi, Lim, Jason C., Miyazaki, Hiroaki, Niisato, Naomi, Marunaka, Yoshinori, Lee, Robert J., Hoff, Henry, Payne, Riley, Demuro, Angelo, Parker, Ian, Mitchell, Claire, Henao-Mejia, Jorge, Tanis, Jessica E., Matsumoto, Ichiro, Tordoff, Michael G., Foskett, J. Kevin
Pubblicato in Neuron (2018)