Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris

Optimal neuronal activity requires that supporting cells provide both efficient nutrient delivery and waste disposal. The incomplete processing of engulfed waste by their lysosomes can lead to accumulation of residual material and compromise their support of neurons. As most degradative lysosomal en...

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Bibliografski detalji
Glavni autori: Guha, Sonia, Baltazar, Gabriel C., Tu, Leigh-Anne, Liu, Ji, Lim, Jason C., Lu, Wennan, Argall, Arthur, Boesze-Battaglia, Kathleen, Laties, Alan M., Mitchell, Claire H.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408960/
https://ncbi.nlm.nih.gov/pubmed/22639870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07804.x
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