p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

Por Leonova, Katerina I., Brodsky, Leonid, Lipchick, Brittany, Pal, Mahadeb, Novototskaya, Liliya, Chenchik, Alex A., Sen, Ganes C., Komarova, Elena A., Gudkov, Andrei V.
Publicado em 2013

A small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice

Por Leonova, Katerina I., Shneyder, Jelena O., Antoch, Marina P., Toshkov, Illia A., Novototskaya, Liliya R., Komarov, Pavel G., Komarova, Elena A., Gudkov, Andrei V.
Publicado no Cell Cycle (2010)

Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice

Por Antoch, Marina P., Wrobel, Michelle, Kuropatwinski, Karen K., Gitlin, Ilya, Leonova, Katerina I., Toshkov, Ilia, Gleiberman, Anatoli S., Hutson, Alan D., Chernova, Olga B., Gudkov, Andrei V.
Publicado no Aging (Albany NY) (2017)

Distinguishing the immunostimulatory properties of noncoding RNAs expressed in cancer cells

Por Tanne, Antoine, Muniz, Luciana R., Puzio-Kuter, Anna, Leonova, Katerina I., Gudkov, Andrei V., Ting, David T., Monasson, Rémi, Cocco, Simona, Levine, Arnold J., Bhardwaj, Nina, Greenbaum, Benjamin D.
Publicado no Proc Natl Acad Sci U S A (2015)

Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells

Por Hall, Brandon M., Balan, Vitaly, Gleiberman, Anatoli S., Strom, Evguenia, Krasnov, Peter, Virtuoso, Lauren P., Rydkina, Elena, Vujcic, Slavoljub, Balan, Karina, Gitlin, Ilya, Leonova, Katerina, Polinsky, Alexander, Chernova, Olga B., Gudkov, Andrei V.
Publicado no Aging (Albany NY) (2016)

Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion

Por Mannava, Sudha, Moparthy, Kalyana C., Wheeler, Linda J., Leonova, Katerina I., Wawrzyniak, Joseph A., Bianchi-Smiraglia, Anna, Berman, Albert E., Flanagan, Sheryl, Shewach, Donna S., Zeitouni, Nathalie C., Gudkov, Andrei V., Mathews, Christopher K., Nikiforov, Mikhail A.
Publicado em 2012

p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli

Por Hall, Brandon M., Balan, Vitaly, Gleiberman, Anatoli S., Strom, Evguenia, Krasnov, Peter, Virtuoso, Lauren P., Rydkina, Elena, Vujcic, Slavoljub, Balan, Karina, Gitlin, Ilya I., Leonova, Katerina I., Consiglio, Camila R., Gollnick, Sandra O., Chernova, Olga B., Gudkov, Andrei V.
Publicado no Aging (Albany NY) (2017)

Nrf2 amplifies oxidative stress via induction of Klf9

Por Zucker, Shoshanna N., Fink, Emily E., Bagati, Archis, Mannava, Sudha, Bianchi-Smiraglia, Anna, Bogner, Paul N., Wawrzyniak, Joseph A., Foley, Colleen, Leonova, Katerina I., Grimm, Melissa J., Moparthy, Kalyana, Ionov, Yurij, Wang, Jianmin, Liu, Song, Sexton, Sandra, Kandel, Eugene S., Bakin, Andrei V., Zhang, Yuesheng, Kaminski, Naftali, Segal, Brahm H., Nikiforov, Mikhail A.
Publicado em 2014

Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist

Por Burdelya, Lyudmila G., Brackett, Craig M., Kojouharov, Bojidar, Gitlin, Ilya I., Leonova, Katerina I., Gleiberman, Anatoli S., Aygun-Sunar, Semra, Veith, Jean, Johnson, Christopher, Haderski, Gary J., Stanhope-Baker, Patricia, Allamaneni, Shyam, Skitzki, Joseph, Zeng, Ming, Martsen, Elena, Medvedev, Alexander, Scheblyakov, Dmitry, Artemicheva, Nataliya M., Logunov, Denis Y., Gintsburg, Alexander L., Naroditsky, Boris S., Makarov, Sergei S., Gudkov, Andrei V.
Publicado em 2013