Pharmacological modulators of the circadian clock as potential therapeutic drugs

por Antoch, Marina P., Chernov, Mikhail V.
Publicado 2009

Pharmacological modulators of the circadian clock as potential therapeutic drugs: focus on genotoxic/anticancer therapy

por Antoch, Marina P., Kondratov, Roman V.
Publicado 2013

Circadian Clock Genes as Modulators of Sensitivity to Genotoxic Stress

por Antoch, Marina P., Kondratov, Roman V., Takahashi, Joseph S.
Publicado 2005

Deficiency in PER proteins has no effect on the rate of spontaneous and radiation-induced carcinogenesis

por Antoch, Marina P, Toshkov, Ilia, Kuropatwinski, Karen K, Jackson, Marilyn
Publicado 2013

The Mouse Clock Locus: Sequence and Comparative Analysis of 204 Kb from Mouse Chromosome 5

por Wilsbacher, Lisa D., Sangoram, Ashvin M., Antoch, Marina P., Takahashi, Joseph S.
Publicado 2000

Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1

por Kondratov, Roman V., Vykhovanets, Olena, Kondratova, Anna A., Antoch, Marina P.
Publicado 2009

A serine cluster mediates BMAL-dependent CLOCK phosphorylation and degradation

por Spengler, Mary L., Kuropatwinski, Karen K., Schumer, Molly, Antoch, Marina P.
Publicado 2009

Circadian clock proteins control adaptation to novel environment and memory formation

por A.Kondratova, Anna, V.Dubrovsky, Yuliya, Antoch, Marina P., Kondratov, Roman V.
Publicado 2010

Daily rhythms are retained both in spontaneously developed sarcomas and in xenografts grown in immunocompromised SCID mice

por Comas, Maria, Kuropatwinski, Karen K., Wrobel, Michelle, Toshkov, Ilia, Antoch, Marina P.
Publicado en Chronobiol Int (2014)

Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock

por Kondratov, Roman V., Kondratova, Anna A., Gorbacheva, Victoria Y., Vykhovanets, Olena V., Antoch, Marina P.
Publicado 2006

Tissue-Specific Changes in Molecular Clocks During the Transition from Pregnancy to Lactation in Mice

por Casey, Theresa M., Crodian, Jennifer, Erickson, Emily, Kuropatwinski, Karen K., Gleiberman, Anatoli S., Antoch, Marina P.
Publicado 2014

The orphan receptor Rev-erbα gene is a target of the circadian clock pacemaker

por Triqueneaux, Gérard, Thenot, Sandrine, Kakizawa, Tomoko, Antoch, Marina P, Safi, Rachid, Takahashi, Joseph S, Delaunay, Franck, Laudet, Vincent
Publicado 2004

BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system

por Kondratov, Roman V., Chernov, Mikhail V., Kondratova, Anna A., Gorbacheva, Victoria Y., Gudkov, Andrei V., Antoch, Marina P.
Publicado 2003

Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex

por Gorbacheva, Victoria Y., Kondratov, Roman V., Zhang, Renliang, Cherukuri, Srujana, Gudkov, Andrei V., Takahashi, Joseph S., Antoch, Marina P.
Publicado 2005

BMAL1-dependent regulation of the mTOR signaling pathway delays aging

por Khapre, Rohini V., Kondratova, Anna A., Patel, Sonal, Dubrovsky, Yuliya, Wrobel, Michelle, Antoch, Marina P., Kondratov, Roman V.
Publicado 2014

Metabolic clock generates nutrient anticipation rhythms in mTOR signaling

por Khapre, Rohini V., Patel, Sonal A., Kondratova, Anna A., Chaudhary, Amol, Velingkaar, Nikkhil, Antoch, Marina P., Kondratov, Roman V.
Publicado 2014

Positional Syntenic Cloning and Functional Characterization of the Mammalian Circadian Mutation tau

por Lowrey, Phillip L., Shimomura, Kazuhiro, Antoch, Marina P., Yamazaki, Shin, Zemenides, Peter D., Ralph, Martin R., Menaker, Michael, Takahashi, Joseph S.
Publicado 2000

New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53(−/−) mice by delaying carcinogenesis

por Comas, Maria, Toshkov, Ilia, Kuropatwinski, Karen K., Chernova, Olga B., Polinsky, Alexander, Blagosklonny, Mikhail V., Gudkov, Andrei V., Antoch, Marina P.
Publicado 2012

Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis

por Antoch, Marina P., Gorbacheva, Victoria Y., Vykhovanets, Olena, Toshkov, Illia A., Kondratov, Roman V., Kondratova, Anna A., Lee, Choogon, Nikitin, Alexander Yu.
Publicado 2008

Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice

por Komarova, Elena A., Antoch, Marina P., Novototskaya, Liliya R., Chernova, Olga B., Paszkiewicz, Geraldine, Leontieva, Olga V., Blagosklonny, Mikhail V., Gudkov, Andrei V.
Publicado 2012