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Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis

The mammalian circadian system has been implicated in the regulation of various biological processes including those involved in genotoxic stress responses and tumor suppression. Here we report that mice with the functional deficiency in circadian transcription factor CLOCK (Clock/Clock mutant mice)...

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Detalhes bibliográficos
Main Authors: Antoch, Marina P., Gorbacheva, Victoria Y., Vykhovanets, Olena, Toshkov, Illia A., Kondratov, Roman V., Kondratova, Anna A., Lee, Choogon, Nikitin, Alexander Yu.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744375/
https://ncbi.nlm.nih.gov/pubmed/18418054
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