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Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis

The mammalian circadian system has been implicated in the regulation of various biological processes including those involved in genotoxic stress responses and tumor suppression. Here we report that mice with the functional deficiency in circadian transcription factor CLOCK (Clock/Clock mutant mice)...

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Bibliographische Detailangaben
Hauptverfasser: Antoch, Marina P., Gorbacheva, Victoria Y., Vykhovanets, Olena, Toshkov, Illia A., Kondratov, Roman V., Kondratova, Anna A., Lee, Choogon, Nikitin, Alexander Yu.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744375/
https://ncbi.nlm.nih.gov/pubmed/18418054
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