p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli

Constitutive p16(Ink4a) expression, along with senescence-associated β-galactosidase (SAβG), are commonly accepted biomarkers of senescent cells (SCs). Recent reports attributed improvement of the healthspan of aged mice following p16(Ink4a)-positive cell killing to the eradication of accumulated SC...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Aging (Albany NY)
Asıl Yazarlar: Hall, Brandon M., Balan, Vitaly, Gleiberman, Anatoli S., Strom, Evguenia, Krasnov, Peter, Virtuoso, Lauren P., Rydkina, Elena, Vujcic, Slavoljub, Balan, Karina, Gitlin, Ilya I., Leonova, Katerina I., Consiglio, Camila R., Gollnick, Sandra O., Chernova, Olga B., Gudkov, Andrei V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611982/
https://ncbi.nlm.nih.gov/pubmed/28768895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101268
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